Results 31 to 40 of about 317,105 (146)
Ceramics, 2023 This paper investigates new approaches for the blending and plastification of ceramic powder with a binder to form fused deposition of ceramic (FDC) feedstock.
Thomas Heim, Frank Kern
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Evaluation of Binders in Twin-Screw Wet Granulation
Pharmaceutics, 2021 The binders povidone (Kollidon 30), copovidone (Kollidon VA64), hypromellose (Pharmacoat 606), and three types of hyprolose (HPC SSL-SFP, HPC SSL, and HPC SL-FP) were evaluated regarding their suitability in twin-screw wet granulation.
Claudia Köster +2 more
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British Journal of Pharmacy, 2022 The pharmaceutical industry has a growing interest in continuous manufacturing, particularly for high-volume dosage forms such as solid oral tablets. This is driven by the obvious benefits such as small footprint, batch size flexibility, the relative ...
Valentyn Mohylyuk +4 more
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Macromol, 2021 High-molecular-weight hypromellose (HPMC) and hydroxypropyl cellulose (HPC) are widely known, extended-release polymers. Conventional high-molecular-weight HPMCs are preferred in extended-release applications but not widely used in twin-screw melt ...
Amol Batra +9 more
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Solid–liquid transport in a modified co-rotating twin-screw extruder-dynamic simulator and experimental validations [PDF]
, 2004 This work presents a dynamic transport model of a solid–liquid media through a twin-screw extruder (TSE). The application under consideration is the solid–liquid extraction of solute from raw plant substrate.
Prat, Laurent E. +4 more
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Continuous Melt Granulation for Taste-Masking of Ibuprofen
Pharmaceutics, 2021 Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
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TWIN SCREW WET AND DRY GRANULATION [PDF]
, 2017 Twin screw granulation has gained wide interest by pharmaceutical manufacturing and the industry is still trying to expand its application. This thesis will further explore this technique and try to develop a new granulation strategy based on similar ...
Liu, Yang
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Pharmaceutics, 2023 The pharmaceutical industry is in the midst of a transition from traditional batch processes to continuous manufacturing. However, the challenges in making this transition vary depending on the selected manufacturing process.
Seth P. Forster +4 more
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Analysing the effect of screw configuration using a stochastic twin-screw granulation model [PDF]
, 2019 © 2019 Elsevier Ltd In this work, a framework for modelling twin-screw granulation processes with variable screw configurations using a high-dimensional stochastic population balance method is presented.
McGuire, Andrew D. +7 more
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Quantitative Assessment of Mass Flow Boundaries in Continuous Twin-screw Granulation
CHIMIA, 2016 In pharmaceutical manufacturing, there is an increasing interest in continuous manufacturing. As an example for fast continuous processes in general of considerable complexity, this study was focussed on improving the understanding of twin-screw
Adrian Schmidt +4 more
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