Results 31 to 40 of about 639 (150)
Ceramics, 2023 This paper investigates new approaches for the blending and plastification of ceramic powder with a binder to form fused deposition of ceramic (FDC) feedstock.
Thomas Heim, Frank Kern
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British Journal of Pharmacy, 2022 The pharmaceutical industry has a growing interest in continuous manufacturing, particularly for high-volume dosage forms such as solid oral tablets. This is driven by the obvious benefits such as small footprint, batch size flexibility, the relative ...
Valentyn Mohylyuk +4 more
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Macromol, 2021 High-molecular-weight hypromellose (HPMC) and hydroxypropyl cellulose (HPC) are widely known, extended-release polymers. Conventional high-molecular-weight HPMCs are preferred in extended-release applications but not widely used in twin-screw melt ...
Amol Batra +9 more
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Distribution of binder in granules produced by means of twin screw granulation [PDF]
International Journal of Pharmaceutics, 2014 According to the quality by design principle processes may not remain black-boxes and full process understanding is required. The granule size distribution of granules produced via twin screw granulation is often found to be bimodal. The aim of this study was to gain a better understanding of binder distribution within granules produced via twin screw ...
Margot Fonteyne +7 more
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Continuous Melt Granulation for Taste-Masking of Ibuprofen
Pharmaceutics, 2021 Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
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Pharmaceutics, 2023 The pharmaceutical industry is in the midst of a transition from traditional batch processes to continuous manufacturing. However, the challenges in making this transition vary depending on the selected manufacturing process.
Seth P. Forster +4 more
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Twin-screw granulation – a systematic analysis of process parameters
British Journal of Pharmacy, 2018 Twin-screw granulation has a significant advantage over traditional granulation methods leading to the possibility of continuous manufacturing. Although this technology has drawn attention in recent years, the general understanding of the process is ...
Margarethe Richter
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Quantitative Assessment of Mass Flow Boundaries in Continuous Twin-screw Granulation
CHIMIA, 2016 In pharmaceutical manufacturing, there is an increasing interest in continuous manufacturing. As an example for fast continuous processes in general of considerable complexity, this study was focussed on improving the understanding of twin-screw
Adrian Schmidt +4 more
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Pharmaceutics, 2021 Recently, the pharmaceutical industry has undergone changes in the production of solid oral dosages from traditional inefficient and expensive batch production to continuous manufacturing.
Ana Alejandra Barrera Jiménez +4 more
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Pharmaceutics, 2022 Twin screw granulation (TSG) is a continuous wet granulation technique that is used widely across different solid manufacturing industries. The TSG has been recognized to have numerous advantages due to its modular design and continuous manufacturing ...
Lalith Kotamarthy +2 more
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