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Bacillus anthracis is a spore-forming bacterium that causes devastating infections and has been used as a bioterror agent. This pathogen can survive hostile environments through the signaling activity of two-component systems, which couple environmental ...
Clare L. Laut +7 more
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The nitrogen (N) status transduced via the NtrBC two-component system is a major signaling cue in the root nodule endosymbiosis of diazotrophic rhizobia with legumes.
Natalia I. García-Tomsig +6 more
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The Pleiotropic Two-Component Regulatory System PhoP-PhoQ [PDF]
PhoP-PhoQ is a two-component system that governs virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities in several gram-negative species. It consists of the inner membrane sensor PhoQ and the cytoplasmic regulator PhoP.
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Control of CydB and GltA1 Expression by the SenX3 RegX3 Two Component Regulatory System of Mycobacterium tuberculosis [PDF]
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Madiraju, MV +9 more
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Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system [PDF]
The EnvZ/OmpR system in Escherichia coli , which regulates the expression of the porins OmpF and OmpC, is one of the simplest and best-characterized examples of two-component signaling.
Eric, Batchelor, Mark, Goulian
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Characterization of a temperature-responsive two component regulatory system from the Antarctic archaeon, Methanococcoides burtonii [PDF]
Cold environments dominate the Earth's biosphere and the resident microorganisms play critical roles in fulfilling global biogeochemical cycles. However, only few studies have examined the molecular basis of thermosensing; an ability that microorganisms ...
Curmi, PMG ; https://orcid.org/ +9 more
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Escherichia coli uses two-component systems (TCSs) to respond to environmental signals. TCSs affect gene expression and are parts of E. coli’s global transcriptional regulatory network (TRN). Here, we identified the regulons of five TCSs in E.
Kumari Sonal Choudhary +7 more
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MxtR/ErdR is a two-component system that has been previously described as a regulator of the utilization of acetate in Vibrio cholerae and in some Pseudomonas species.
Tania Henríquez +5 more
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Two-Component Regulatory Systems of Mycobacteria
ABSTRACT Two-component regulatory systems (2CRSs) are widely used by bacteria to sense and respond to environmental stimuli with coordinated changes in gene expression. Systems are normally comprised of a sensory kinase protein that activates a transcriptional regulator by phosphorylation.
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It might take Two-Component Systems to combat super bugs [PDF]
Different Two-Component regulatory systems (TCSs) have been reported to play a major role in the regulation of antibiotic resistance in Acinetobacter baumannii, including our last resort polymyxins drugs.
Yasser Alsaadi (8955941)
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