Results 31 to 40 of about 407,697 (279)

Immediate and heterogeneous response of the LiaFSR two-component system of Bacillus subtilis to the peptide antibiotic bacitracin. [PDF]

, 2013
Two-component signal transduction systems are one means of bacteria to respond to external stimuli. The LiaFSR two-component system of Bacillus subtilis consists of a regular two-component system LiaRS comprising the core Histidine Kinase (HK) LiaS and ...
Madeleine Leisner (104026), Leisner, Madeleine, Carolin Höfler, Carolin Höfler (104020), Madeleine Leisner, Andreas Mader, Thorsten Mascher, Sara Kesel (104013), Höfler, Carolin, Sara Kesel, Andreas Mader (104017), Mader, Andreas, Thorsten Mascher (104023), Kesel, Sara, Mascher, Thorsten   +14 more
core   +1 more source

Transmembrane Prolines Mediate Signal Sensing and Decoding in Bacillus subtilis DesK Histidine Kinase

mBio, 2019
Environmental awareness is an essential attribute of all organisms. The homeoviscous adaptation system of Bacillus subtilis provides a powerful experimental model for the investigation of stimulus detection and signaling mechanisms at the molecular level.
Pilar Fernández, Lucía Porrini, Daniela Albanesi, Luciano A. Abriata, Matteo Dal Peraro, Diego de Mendoza, María C. Mansilla   +6 more
doaj   +1 more source

The KdpD/KdpE two-component system : integrating K+ homeostasis and virulence [PDF]

, 2013
The two-component system (TCS) KdpD/KdpE, extensively studied for its regulatory role in potassium (K+) transport, has more recently been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria ...
Freeman, Zoë N., Zoë N Freeman, Steve Dorus, Waterfield, Nicholas R., Dorus, Steve, Nicholas R Waterfield   +5 more
core   +1 more source

Novel two-component regulatory systems play a role in biofilm formation of Lactobacillus reuteri rodent isolate 100-23 [PDF]

, 2014
his study characterized the two-component regulatory systems encoded by bfrKRT and cemAKR, and assessed their influence on biofilm formation by Lactobacillus reuteri 100-23. A method for deletion of multiple genes was employed to disrupt the genetic loci
Gänzle, Michael G., Su, Marcia Shu-Wei
core   +1 more source

Characterization of the two component regulatory system PhoPR in Mycobacterium bovis [PDF]

Veterinary Microbiology, 2018
Mycobacterium bovis is the causative agent of bovine tuberculosis and is a member of Mycobacterium tuberculosis complex, which causes tuberculosis in a number of mammals including humans. Previous studies have shown that the genes encoding the two-component system PhoPR, which regulates several genes involved in the virulence of M.
Elizabeth A. García, Federico C. Blanco, María M. Bigi, Cristina L. Vazquez, Marina A. Forrellad, Rosana V. Rocha, Paul Golby, Marcelo A. Soria, Fabiana Bigi   +8 more
openaire   +3 more sources

Split histidine kinases enable ultrasensitivity and bistability in two-component signaling networks [PDF]

, 2012
Bacteria sense and respond to their environment through signaling cascades generally referred to as two-component signaling networks. These networks comprise histidine kinases and their cognate response regulators.
Steven L Porter, Orkun S. Soyer (242985), Munia Amin, Amin, M, Orkun S. Soyer, Soyer, Orkun S., Steven L. Porter, Amin Munia, Munia Amin (386302), Amin, Munia, Porter, SL, Porter Steven L., Soyer Orkun S., Soyer, OS, Steven L. Porter (243401), Porter, Steven L., Orkun S Soyer   +16 more
core   +1 more source

A Two-component Regulatory System Involved in Clavulanic Acid Production [PDF]

The Journal of Antibiotics, 2008
A pair of genes encoding the bacterial two-component regulatory system, orf22 and orf23, was found next to the clavulanic acid gene cluster of Streptomyces clavuligerus NRRL3585. Orf23 was deleted for the construction of S. clavuligerus/Deltaorf23. Although growth and morphological analyses showed no differences between S.
Hum Nath, Jnawali, Tae-Jin, Oh, Kwangkyoung, Liou, Byoung Chul, Park, Jae Kyung, Sohng   +4 more
openaire   +2 more sources

Modulation of the Regulatory Activity of Bacterial Two-component Systems by SlyA [PDF]

Journal of Biological Chemistry, 2008
Activation of the transcriptional regulator SlyA by the PhoP/PhoQ two-component system controls intracellular expression of numerous factors influencing Salmonella virulence. By dissecting the SlyA regulon using stable isotope labeling with amino acids in cell culture analysis, we found that SlyA enhances overall transcription of PhoP-activated loci ...
Haowei, Song, Wei, Kong, Natasha, Weatherspoon, Guozheng, Qin, William, Tyler, John, Turk, Roy, Curtiss, Yixin, Shi   +7 more
openaire   +2 more sources

Bacterial adaptation through distributed sensing of metabolic fluxes [PDF]

, 2010
The recognition of carbon sources and the regulatory adjustments to recognized changes are of particular importance for bacterial survival in fluctuating environments.
J. B. Zaugg, Heinemann, M.,, Kotte, Oliver,, M. Heinemann, O. Kotte, Heinemann, Matthias, Matthias Heinemann, Zaugg, Judith B., Zaugg, Judith B.,, Heinemann, Matthias,, Kotte, Oliver, Heinemann, Matthias; id_orcid, Judith B Zaugg, Kotte, O.,, Oliver Kotte, Zaugg, J.B.,   +15 more
core   +1 more source

Loss of the Two-Component System TctD-TctE in Pseudomonas aeruginosa Affects Biofilm Formation and Aminoglycoside Susceptibility in Response to Citric Acid

mSphere, 2019
The two-component system TctD-TctE is important for regulating the uptake of tricarboxylic acids in Pseudomonas aeruginosa. TctD-TctE accomplishes this through derepression of the gene opdH, which encodes a tricarboxylic acid-specific porin.
Patrick K. Taylor, Li Zhang, Thien-Fah Mah   +2 more
doaj   +1 more source