Results 51 to 60 of about 5,397,691 (379)

Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach

open access: yesDiabetes Care, 2012
Glycemic management in type 2 diabetes mellitus has become increasingly complex and, to some extent, controversial, with a widening array of pharmacological agents now available (1–5), mounting concerns about their potential adverse effects and new ...
S. Inzucchi   +9 more
semanticscholar   +1 more source

Approach to: Type 2 diabetes management

open access: yesMcGill Journal of Medicine, 2021
Type 2 Diabetes Mellitus (T2DM) is a chronic and insidious disease that is on the rise worldwide. Diabetes pharmacotherapy is complex and varied, and recent studies of novel antihyperglycemic drugs have raised important considerations for the management ...
Susan Joanne Wang
doaj   +1 more source

Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.

open access: yesNew England Journal of Medicine, 2016
BACKGROUND Diabetes confers an increased risk of adverse cardiovascular and renal events. In the EMPA-REG OUTCOME trial, empagliflozin, a sodium-glucose cotransporter 2 inhibitor, reduced the risk of major adverse cardiovascular events in patients with ...
C. Wanner   +9 more
semanticscholar   +1 more source

Pathophysiology of Type 2 Diabetes Mellitus

open access: yesInternational Journal of Molecular Sciences, 2020
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to ...
U. Galicia-Garcia   +7 more
semanticscholar   +1 more source

Type-2 diabetes

open access: yesAnnals of Internal Medicine
Type 2 diabetes (T2D) is a prevalent disease that increases risk for vascular, renal, and neurologic complications. Prevention and treatment of T2D and its complications are paramount. Many advancements in T2D care have emerged over the past 5 years, including increased understanding of the importance of early intensive glycemic control, mental health,
Skoradal, May-Britt   +4 more
openaire   +5 more sources

The effects of Tai Chi on peripheral somatosensation, balance, and fitness in Hispanic older adults with type 2 diabetes:a pilot and feasibility study [PDF]

open access: yes, 2015
Peripheral neuropathy and loss of somatosensation in older adults with type 2 diabetes can increase risk of falls and disability. In nondiabetic older adult population Tai Chi has been shown to enhance balance and fitness through improvements in ...
Cavegn, Elisabeth I., Riskowski, Jody
core   +4 more sources

Cohort profile: the ‘Biomarkers of heterogeneity in type 1 diabetes’ study—a national prospective cohort study of clinical and metabolic phenotyping of individuals with long-standing type 1 diabetes in the Netherlands

open access: yesBMJ Open
Purpose The ‘Biomarkers of heterogeneity in type 1 diabetes’ study cohort was set up to identify genetic, physiological and psychosocial factors explaining the observed heterogeneity in disease progression and the development of complications in people ...
  +31 more
doaj   +1 more source

IL-6 and Type 2 Diabetes

open access: yesمجلة كلية الطب, 2010
Background: Interleukin -6 (IL-6) as the key mediator of the acute phase reaction is of interest .elevated protein concentrations of IL-6 in the blood have been shown in patients with type 2 diabetes. This study aimed to investigate the association of IL-
Maha F. Almelan
doaj   +1 more source

The association between neighbourhood greenspace and type 2 diabetes in a large cross-sectional study [PDF]

open access: yes, 2014
Objective: To investigate the relationship between neighbourhood greenspace and type 2 diabetes. Design: Cross-sectional. Setting: 3 diabetes screening studies conducted in Leicestershire, UK in 2004–2011.
Astell-Burt   +38 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

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