Results 141 to 150 of about 707 (287)

Phospholipase C produced by Clostridium botulinum types C and D: comparison of gene, enzymatic, and biological activities with those of Clostridium perfringens alpha-toxin.

open access: yesActa medica Okayama, 2013
Clostridium botulinum type C and D strains recently have been found to produce PLC on egg yolk agar plates. To characterize the gene, enzymatic and biological activities of C. botulinum PLCs (Cb-PLCs), the cb-plc genes from 8 strains were sequenced, and 1 representative gene was cloned and expressed as a recombinant protein. The enzymatic and hemolytic
Fatmawati, Ni Nengah Dwi   +8 more
openaire   +3 more sources

Identification of genes involved in macrophage activation and effector functions against intracellular pathogens

open access: yes, 2006
Includes bibliographical references.This dissertation addressed the hypothesis that macrophages have an alternative killing mechanism that is independent of superoxide and nitric oxide but dependent on IFN-γ, TNF and C/EBPβ.
Schwegmann, Anita Ruth
core  

Human neutrophil migration in vitro induced by secretory phospholipases A(2): a role for cell surface glycosaminoglycans

open access: yes, 2002
The purpose of this study was to examine the ability of type I- (porcine pancreas and Naja mocambique mocambique venom), type II- (bothropstoxin-I, bothropstoxin-II, and piratoxin-I).
Antunes, E.   +8 more
core   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

open access: yesInterdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi   +18 more
wiley   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

open access: yesiRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li   +4 more
wiley   +1 more source

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