Clinical, genetic and molecular aspects of membranous nephropathy
, 2011 Membranous Nephropathy (MN) is one of the leading causes of end-stage renal disease (ESRD). MN is an autoimmune disease in which autoantibodies target antigens at the level of the glomerular basement membrane.
Stanescu, H.C.
core
Is dipalmitoylphosphatidylcholine a substrate for convertase?
, 2000 Convertase has homology with carboxylesterases, but its substrate(s) is not known. Accordingly, we determined whether dipalmitoylphosphatidylcholine (DPPC), the major phospholipid in surfactant, was a substrate for convertase.
Andelle Teng +4 more
core +1 more source
Food Safety and Health, EarlyView.Representation of grass pea consumption in drought‐stricken sub‐Saharan Africa sustains nutrition, but excess β‐ODAP exposure due to multiple reasons triggers neurolathyrism, a progressive neurotoxic disorder. ABSTRACT Neurolathyrism is a progressive motor neuron disease due to the consumption of Lathyrus sativus (grass pea) over long periods.
Biruk Demisse Ayalew +12 more
wiley +1 more source
The characterisation of Plc1 : a phospholipase C enzyme identified in the fission yeast Schizosaccharomyces pombe [PDF]
The plc1 gene product (Plc1) of the fission yeast Schizosaccharomycespombe (Sz. pombe) encodes a phosphoinositide-specific phospholipase C (PLC) and most closely resembles the δ class of the PLC isozymes.
Brind, Robert Ian
core
Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Cellular & Molecular Biology LettersThe skin is a barrier that protects the human body against environmental factors (physical, including solar radiation, chemicals, and pathogens). The integrity and, consequently, the effective metabolic activity of skin cells is ensured by the cell ...
Michał Biernacki +1 more
doaj +1 more source
Cloning and characterisation of phospholipase C X-domain containing proteins (PLCXDs)
, 2015 Members of the phosphoinositide-specific phospholipase C (PI-PLC) enzyme family play a fundamental role in cell signalling pathways by regulating cytosolic calcium and/or the activity of several protein kinases. This thesis reports the identification,
Gellatly, Steven Alexander
core
, 2009 Os envenenamentos causados pelas serpentes do gênero Bothrops são os mais importantes do ponto de vista médico e econômico na América Central. Dentre estas, a serpente Bothrops asper é responsável por 90% dos envenenamentos ofídicos registrados no Panamá
Aristides Quintero Rueda +1 more
core +1 more source
Demonstration of Functionally Different Interactions between Phospholipase C-γ and the Two Types of Platelet-derived Growth Factor Receptors [PDF]
, 1995 Eewa Nånberg +8 more
openalex +1 more source
Aggretin, a Heterodimeric C-type Lectin from Calloselasma rhodostoma (Malayan Pit Viper), Stimulates Platelets by Binding to α2β1 Integrin and Glycoprotein Ib, Activating Syk and Phospholipase Cγ2, but Does Not Involve the Glycoprotein VI/Fc Receptor γ Chain Collagen Receptor [PDF]
, 2001 Alexei Navdaev +7 more
openalex +1 more source
C‐type lectin‐like domain and fibronectin‐like type II domain of phospholipase A2 receptor 1 modulate binding and migratory responses to collagen [PDF]
, 2015 Soichiro Takahashi +7 more
openalex +1 more source