Results 161 to 170 of about 533,494 (308)

Role of Angiotensin II Type 1A Receptor Phosphorylation, Phospholipase D, and Extracellular Calcium in Isoform-specific Protein Kinase C Membrane Translocation Responses [PDF]

open access: hybrid, 2006
Aleksandra Policha   +8 more
openalex   +1 more source

Macromolecular crystallography at Elettra: current and future perspectives

open access: yesJournal of Synchrotron Radiation, EarlyView.
The XRD2 beamline at Elettra‐Sincrotrone Trieste has been in operation since 2018 and is dedicated to macromolecular crystallography for both academic and industrial research, a role partially fulfilled, before 2018, by XRD1, a general‐purpose diffraction beamline.
Raghurama P. Hegde   +13 more
wiley   +1 more source

Genetic and Pharmacological Inhibition of Metabotropic Glutamate Receptor Signalling Extends Lifespan in Drosophila

open access: yesAging Cell, EarlyView.
We show that genetic and pharmacological inhibition of the metabotropic glutamate receptor, DmGluRA extends Drosophila lifespan, improves stress tolerance and alters early‐life locomotion. Several markers indicative of reduced ribosomal biogenesis, a hallmark of longevity, were also detected in these flies.
Cui Guan   +4 more
wiley   +1 more source

Dipeptidyl peptidase-IV inhibitors used in type-2 diabetes inhibit a phospholipase C: a case of promiscuous scaffolds in proteins [PDF]

open access: gold, 2015
Sandeep Chakraborty   +9 more
openalex   +1 more source

Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians

open access: yesAging Cell, EarlyView.
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien   +11 more
wiley   +1 more source

Receptor-evoked Cl- current in Xenopus oocytes is mediated through a beta-type phospholipase C. Cloning of a new form of the enzyme.

open access: hybrid, 1993
Hui Ma   +5 more
openalex   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from <i>Loxosceles</i> spiders. [PDF]

open access: yesToxicon X
Catalán A   +10 more
europepmc   +1 more source

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