Cloning of the Human Phospholipase C-γ1 Promoter and Identification of a DR6-type Vitamin D-responsive Element [PDF]
Journal of Biological Chemistry, 1997 The 5'-flanking region of the human phospholipase C-gamma1 gene was isolated from a human P1 genomic DNA library. The S1-nuclease mapping and primer extension analysis revealed that there is a single transcriptional start site located at 135 bases upstream from the translation start codon in the human phospholipase C-gamma1 gene.
Zhongjian Xie, Daniel D. Bikle
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Phylogenetic analysis of phospholipase C genes from Clostridium perfringens types A to E and Clostridium novyi [PDF]
Journal of Bacteriology, 1995 The phylogenetic interrelationships between strains of 5 toxin types (A to E) of Clostridium perfringens were examined by analysis of differences in the nucleotide sequences of phospholipase C genes (plc genes) among 10 strains, including 3 strains for which the plc gene sequences have been previously reported.
Ken‐Ichiro Tsutsui +7 more
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Purification of two distinct types of phosphoinositide-specific phospholipase C from rat liver. Enzymological and structural studies [PDF]
Biochemical Journal, 1988 Two kinds of phosphoinositide-specific phospholipase C (PLC) were purified from rat liver by acid precipitation and several steps of column chromatography. About 50% of the activity could be precipitated when the pH of the liver homogenate was lowered to pH 4.7. The redissolved precipitate yielded two peaks, PLC I and PLC II, in an Affi-gel Blue column,
Osamu Nakanishi +5 more
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Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin [PDF]
Cellular & Molecular Biology LettersThe skin is a barrier that protects the human body against environmental factors (physical, including solar radiation, chemicals, and pathogens). The integrity and, consequently, the effective metabolic activity of skin cells is ensured by the cell ...
Michał Biernacki +1 more
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Mechanisms of Phospholipase C Activation by the Vasoactive Intestinal Polypeptide/Pituitary Adenylate Cyclase-Activating Polypeptide Type 2 Receptor [PDF]
Endocrinology, 2001 The vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide type 2 (VPAC(2)) receptor was shown to induce both [(3)H]inositol phosphate ([(3)H]InsP)and cAMP production in transfected COS7 cells and in GH(3) cells where it is natively expressed.
Chris Mackenzie
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Hydrolysis of Phospholipids by phospholipase C in intact cells of wild‐type and envelope mutants of Escherichia coli K12 [PDF]
FEBS Letters, 1981 Zdena Stárková +2 more
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Journal of Fisheries and Marine Sciences Education, 2016 Soo-Ji Woo, Hyung Ho Lee, Joon-Ki Chung
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Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]
PeerJ, 2014 Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma +3 more
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background Snake venoms are complex mixtures of toxic proteins or peptides encoded by various gene families that function synergistically to incapacitate prey.
Xuekui Nie +7 more
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Molecules, 2023 Secreted phospholipases A2 are snake-venom proteins with many biological activities, notably anti-tumor activity. Phospholipases from the same snake type but different geographical locations have shown similar biochemical and biological activities with ...
Mona Alonazi +6 more
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