Results 31 to 40 of about 1,747,398 (243)

A transcriptomic analysis of gene expression in the venom gland of the snake Bothrops alternatus (urutu)

BMC Genomics, 2010
Background The genus Bothrops is widespread throughout Central and South America and is the principal cause of snakebite in these regions. Transcriptomic and proteomic studies have examined the venom composition of several species in this genus, but many
Menossi Marcelo, Vidal Ramon O, Del Bem Luiz, Torres Tatiana T, Costa Gustavo GL, Da Silva Márcio J, Cardoso Kiara C, Hyslop Stephen   +7 more
doaj   +1 more source

Two distinct phospholipases C of Listeria monocytogenes induce ceramide generation, nuclear factor-kappa B activation, and E-selectin expression in human endothelial cells.

Journal of Immunology, 1998
Infection of endothelial cells by Listeria monocytogenes is an essential step in the pathogenesis of listeriosis. We recently reported that L. monocytogenes induces up-regulation of E-selectin and other endothelial adhesion molecules and subsequent ...
Nicole Schwarzer, R. Nöst, Joachim Seybold, S. Parida, O. Fuhrmann, M. Krüll, Reinhold E. Schmidt, Robert Newton, S. Hippenstiel, E. Domann, Trinad Chakraborty, N. Suttorp   +11 more
semanticscholar   +1 more source

Secretory Phospholipases A2 in Plants [PDF]

, 2019
Secreted phospholipases (sPLA2s) in plants are a growing group of enzymes that catalyze the hydrolysis of sn-2 glycerophospholipids to lysophospholipids and free fatty acids. Until today, around only 20 sPLA2s were reported from plants.
Fidelio, Gerardo Daniel, Mariani, Maria Elisa   +1 more
core   +1 more source

Proteome and Peptidome of Vipera berus berus Venom

Molecules, 2016
Snake venom is a rich source of peptides and proteins with a wide range of actions. Many of the venom components are currently being tested for their usefulness in the treatment of many diseases ranging from neurological and cardiovascular to cancer.
Aleksandra Bocian, Małgorzata Urbanik, Konrad Hus, Andrzej Łyskowski, Vladimír Petrilla, Zuzana Andrejčáková, Monika Petrillová, Jaroslav Legath   +7 more
doaj   +1 more source

Comparative Genome Analysis and Phenotypic Characterization of Clostridium gasigenes CGAS001 Isolated From Chilled Vacuum-Packed Lamb Meat

Frontiers in Microbiology, 2020
Genomic data for psychrophilic bacteria causing blown pack spoilage (BPS) are limited. This study characterizes the genome of a novel Clostridium gasigenes strain CGAS001 isolated from meat juice sample (MJS) of vacuum-packed lamb meat by comparing it ...
Joseph Wambui, Nicole Cernela, Sabrina Corti, Roger Stephan   +3 more
doaj   +1 more source

Comparison of Protein Variation in Protobothrops mucrosquamatus Venom between Northern and Southeast Taiwan and Association with Human Envenoming Effects

Toxins, 2022
Reports of bite from Protobothrops mucrosquamatus (Pmu) are frequent in Taiwan, and its wide-spread distribution and diverse habitats drove us to investigate its envenoming effects and relevant venom variations.
Liao-Chun Chiang, Kun-Yi Chien, Hung-Yuan Su, Yen-Chia Chen, Yan-Chiao Mao, Wen-Guey Wu   +5 more
doaj   +1 more source

Collagen type IV stimulates an increase in intracellular Ca2+ in pancreatic acinar cells via activation of phospholipase C [PDF]

Biochemical Journal, 1994
Intracellular Ca2+ responses to extracellular matrix molecules were studied in suspensions of pancreatic acinar cells loaded with Fura-2. Collagen type I, laminin, fibrinogen and fibronectin were unable to raise cytosolic free Ca2+ concentration ([Ca2+]i), whereas collagen type IV, at concentrations from 5 to 50 micrograms/ml, significantly increased ...
László Somogyi, Zoran Lasić, Slobodan Vukičević, Hrvoje Banfíƈ   +3 more
openalex   +4 more sources

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +3 more sources

Purification of two distinct types of phosphoinositide-specific phospholipase C from rat liver. Enzymological and structural studies [PDF]

Biochemical Journal, 1988
Two kinds of phosphoinositide-specific phospholipase C (PLC) were purified from rat liver by acid precipitation and several steps of column chromatography. About 50% of the activity could be precipitated when the pH of the liver homogenate was lowered to pH 4.7. The redissolved precipitate yielded two peaks, PLC I and PLC II, in an Affi-gel Blue column,
Osamu Nakanishi, Yoshimi Homma, Hiroshi Kawasaki, Yasufumi Emori, Koichi Suzuki, T Takenawa   +5 more
openalex   +4 more sources

Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)* [PDF]

, 2016
Macrophages are important in innate and adaptive immunity. Macrophage participation in inflammation or tissue repair is directed by various extracellular signals and mediated by multiple intracellular pathways.
Ashley, Jason W, Bone, Robert N, Hancock, William D, Nelson, Alexander J, Ramanadham, Sasanka, Tse, Hubert M, Turk, John, Wohltmann, Mary   +7 more
core   +2 more sources