Results 11 to 20 of about 18,200 (209)

Comparative Genome Analysis and Phenotypic Characterization of Clostridium gasigenes CGAS001 Isolated From Chilled Vacuum-Packed Lamb Meat

open access: yesFrontiers in Microbiology, 2020
Genomic data for psychrophilic bacteria causing blown pack spoilage (BPS) are limited. This study characterizes the genome of a novel Clostridium gasigenes strain CGAS001 isolated from meat juice sample (MJS) of vacuum-packed lamb meat by comparing it ...
Joseph Wambui   +3 more
doaj   +1 more source

Comparison of Protein Variation in Protobothrops mucrosquamatus Venom between Northern and Southeast Taiwan and Association with Human Envenoming Effects

open access: yesToxins, 2022
Reports of bite from Protobothrops mucrosquamatus (Pmu) are frequent in Taiwan, and its wide-spread distribution and diverse habitats drove us to investigate its envenoming effects and relevant venom variations.
Liao-Chun Chiang   +5 more
doaj   +1 more source

A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis[S]

open access: yesJournal of Lipid Research, 2009
Human endothelial lipase (EL) is a member of a family of lipases and phospholipases that are involved in the metabolism of plasma lipoproteins. EL displays a preference to hydrolyze lipids in HDL.
Robert J. Brown   +9 more
doaj   +1 more source

The Arabidopsis DREB2 genetic pathway is constitutively repressed by basal phosphoinositide-dependent phospholipase C coupled to diacylglycerol kinase in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2013
Phosphoinositide-dependent phospholipases C (PI-PLCs) are activated in response to various stimuli. They utilize substrates provided by type III-Phosphatidylinositol-4 kinases (PI4KIII) to produce inositol triphosphate and diacylglycerol (DAG) that is ...
Nabila eDjafi   +12 more
doaj   +1 more source

An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells

open access: yesFrontiers in Oncology, 2022
Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a promising target for new anticancer strategies.
Félix A. Urra   +9 more
doaj   +1 more source

Endogenous phospholipase A2 inhibitors in snakes: a brief overview

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2017
The blood plasma of numerous snake species naturally comprises endogenous phospholipase A2 inhibitors, which primarily neutralize toxic phospholipases A2 that may eventually reach their circulation.
Patrícia Cota Campos   +3 more
doaj   +1 more source

The genetics of venom ontogeny in the eastern diamondback rattlesnake (Crotalus adamanteus) [PDF]

open access: yesPeerJ, 2017
The same selective forces that give rise to rapid inter- and intraspecific divergence in snake venoms can also favor differences in venoms across life-history stages.
Darin R. Rokyta   +3 more
doaj   +2 more sources

Biochemistry and toxicology of proteins and peptides purified from the venom of Vipera berus berus

open access: yesToxicon: X, 2022
The isolation and characterization of individual snake venom components is important for a deeper understanding of the pathophysiology of envenomation and for improving the therapeutic procedures of patients. It also opens possibilities for the discovery
Jüri Siigur, PhD, Ene Siigur, PhD
doaj   +1 more source

Proteomics and immunocharacterization of Asian mountain pit viper (Ovophis monticola) venom.

open access: yesPLoS ONE, 2021
The venomic profile of Asian mountain pit viper Ovophis monticola is clarified in the present study. Using mass spectrometry-based proteomics, 247 different proteins were identified in crude venom of O. monticola found in Thailand.
Siravit Sitprija   +10 more
doaj   +1 more source

Natural Compounds Interacting with Nicotinic Acetylcholine Receptors: From Low-Molecular Weight Ones to Peptides and Proteins

open access: yesToxins, 2015
Nicotinic acetylcholine receptors (nAChRs) fulfill a variety of functions making identification and analysis of nAChR subtypes a challenging task. Traditional instruments for nAChR research are d-tubocurarine, snake venom protein α-bungarotoxin (α-Bgt ...
Denis Kudryavtsev   +9 more
doaj   +1 more source

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