Results 51 to 60 of about 32,298 (336)

Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)* [PDF]

, 2016
Macrophages are important in innate and adaptive immunity. Macrophage participation in inflammation or tissue repair is directed by various extracellular signals and mediated by multiple intracellular pathways.
Ashley, Jason W, Bone, Robert N, Hancock, William D, Nelson, Alexander J, Ramanadham, Sasanka, Tse, Hubert M, Turk, John, Wohltmann, Mary   +7 more
core   +2 more sources

Production of Phospholipase C (Alpha-toxin), Haemolysins and Lethal Toxins by Clostridium perfringens Types A to D [PDF]

Journal of General Microbiology, 1976
To obtain high yields of extracellular enzymes and toxins for immunological analysis, type culture collection strains of Clostridium perfringens types A to D and 28 fresh isolates of C. perfringens type A from humans were grown in fermenters under controlled conditions in a pre-reduced proteose peptone medium.
R, Möllby, T, Holme, C E, Nord, C J, Smyth, T, Wadström   +4 more
openaire   +2 more sources

Vipera berus berus Venom from Russia: Venomics, Bioactivities and Preclinical Assessment of Microgen Antivenom

Toxins, 2019
The common European adder, Vipera berus berus, is a medically relevant species, which is widely distributed in Russia and thus, is responsible for most snakebite accidents in Russia.
Ruslan I. Al-Shekhadat, Ksenia S. Lopushanskaya, Álvaro Segura, José María Gutiérrez, Juan J. Calvete, Davinia Pla   +5 more
doaj   +1 more source

Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]

, 2015
Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa, Megighian, Aram, Montecucco, Cesare, Pirazzini, Marco, Rigoni, Michela, Scorzeto, M., Zanetti, Giulia   +6 more
core   +2 more sources

Quantitative Proteomic Analysis of Venoms from Russian Vipers of Pelias Group: Phospholipases A2 are the Main Venom Components

Toxins, 2016
Venoms of most Russian viper species are poorly characterized. Here, by quantitative chromato-mass-spectrometry, we analyzed protein and peptide compositions of venoms from four Vipera species (V. kaznakovi, V. renardi, V. orlovi and V.
Sergey I. Kovalchuk, Rustam H. Ziganshin, Vladislav G. Starkov, Victor I. Tsetlin, Yuri N. Utkin   +4 more
doaj   +1 more source

Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion [PDF]

, 2018
Bio-based production of fatty acids and fatty acid-derived products can enable sustainable substitution of petroleum-derived fuels and chemicals. However, developing new microbial cell factories for producing high levels of fatty acids requires extensive
Ferreira, Raphael, Nielsen, Jens, Siewers, Verena, Teixeiraa, Paulo Goncalves   +3 more
core   +1 more source

Biological and Proteolytic Variation in the Venom of Crotalus scutulatus scutulatus from Mexico

Toxins, 2018
Rattlesnake venoms may be classified according to the presence/absence and relative abundance of the neurotoxic phospholipases A 2 s (PLA 2 s), such as Mojave toxin, and snake venom metalloproteinases (SVMPs).
Miguel Borja, Edgar Neri-Castro, Gamaliel Castañeda-Gaytán, Jason L. Strickland, Christopher L. Parkinson, Juan Castañeda-Gaytán, Roberto Ponce-López, Bruno Lomonte, Alejandro Olvera-Rodríguez, Alejandro Alagón, Rebeca Pérez-Morales   +10 more
doaj   +1 more source

Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications [PDF]

, 2019
Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation and fibrillation makes ...
Alza, Natalia Paola, Conde, Melisa Ailén, Iglesias González, Pablo Andrés, Salvador, Gabriela Alejandra, Uranga, Romina Maria   +4 more
core   +1 more source

Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity in vitro

Toxicon: X
Animal venoms are natural products that have served as a source of novel molecules that have inspired novel drugs for several diseases, including for metabolic diseases such as type-2 diabetes and obesity. From venoms, toxins such as exendin-4 (Heloderma
David Meléndez-Martínez, Erika Ortega-Hernández, Edwin Estefan Reza-Zaldívar, Alejandro Carbajal-Saucedo, Gustavo Arnaud-Franco, Ana Gatica-Colima, Luis Fernando Plenge-Tellechea, Marilena Antunes-Ricardo, Daniel A. Jacobo-Velázquez, Karla Mayolo-Deloisa, Omar Lozano, Marco Rito-Palomares, Jorge Benavides   +12 more
doaj   +1 more source

A cAMP-binding ectoprotein in the yeast Saccharomyces cerevisiae [PDF]

, 1991
tides 10, 593 ...
Achstetter T., Baroni M. D., Behrens M. M., Biilow R., Bregman D. B., Brunton L. L., Cannon J. F., Caras I. W., Caras I. W., Carr S. A., Clegg C., Conzelmann A., Conzelmann A., Corbin J. D., Cross G. A. M., Dallner G., Davitz M. A., Davitz M. A., DeCamilli P., Doering T. L., Edelman A. M., Ferguson M. A. J., Ferguson M. A. J., Ferguson R., Fersht A., Flockart D. A., Gruber W., Hixson C. S., Ishihara M., Jaynes P. K., Johnson K. E., Kamps M. P., Kiibler D., Korc-Grodzicki B., Kunisawa R., Lang B., Lohmann S. M., Lohmann S. M., Low M. G., Low M. G., Matsumoto K., Matsumoto K., Matsumoto K., Matsumoto K., Matsumoto K., Merino A., Mitts M. R., Mostov K. E., Muller G., Muller G., Muller G., Muller G„, Nairn A. C., Nigam S. K., Nigg E. A., Nigg E. A., Olson S., Pall G., Rhee T., Rodel G., Sakar D., Salomon Y., Smith M. E., Srere P. A., Stieger A., Takami N., Thorner J., Toda T., Trams E. G., Uno I., Vai M., Wen T. C., Wingender-Drissen R.   +72 more
core   +3 more sources