Results 111 to 120 of about 1,669,550 (354)

A novel phosphoproteomic landscape evoked in response to type I interferon in the brain and in glial cells

open access: green, 2021
Barney Viengkhou   +4 more
openalex   +1 more source

Type I interferon induces CXCL13 to support ectopic germinal center formation

open access: yesJournal of Experimental Medicine, 2019
Ectopic lymphoid structures form in a wide range of inflammatory conditions, including infection, autoimmune disease, and cancer. In the context of infection, this response can be beneficial for the host: influenza A virus infection–induced pulmonary ...
A. Denton   +10 more
semanticscholar   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

Type I Interferons Promote Severe Disease in a Mouse Model of Lethal Ehrlichiosis [PDF]

open access: bronze, 2014
Yubin Zhang   +4 more
openalex   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

open access: yesAdvanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich   +5 more
wiley   +1 more source

Type I interferons protect neonates from acute inflammation through interleukin 10–producing B cells [PDF]

open access: bronze, 2007
Xiaoming Zhang   +5 more
openalex   +1 more source

Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies [PDF]

open access: gold, 2023
Paul Noe   +12 more
openalex   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

Murine Coronavirus Cell Type Dependent Interaction with the Type I Interferon Response

open access: yesViruses, 2009
Coronaviruses infect many species of animal including humans, causing acute and chronic diseases of many organ systems. Murine coronavirus, mouse hepatitis virus (MHV) infection of the mouse, provides animal models for the study of central nervous system
Susan R. Weiss, Kristine M. Rose
doaj   +1 more source

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