Results 11 to 20 of about 275,498 (259)
Altered collagen I and premature pulmonary embryonic differentiation in patients with OI type II
Physiological Reports, 2023 Pulmonary hypoplasia and respiratory failure are primary causes of death in patients with osteogenesis imperfecta (OI) type II. OI is a genetic skeletal disorder caused by pathogenic variants in genes encoding collagen type I.
S. Storoni +9 more
doaj +1 more source
Type II collagen distribution in rodents [PDF]
The Laryngoscope, 1988 AbstractThe anatomical distribution of type II collagen in animal ears was studied by immunohistochemical techniques, using defined monoclonal antibodies to type II collagen.Type II collagen was observed in the cartilage plate of the auricle and external auditory meatus, tympanic annulus, lamina propria of tympanic membrane (pars tensa), interossicular
T J, Yoo, K, Tomoda
openaire +2 more sources
Association of Chondroadherin with Collagen Type II [PDF]
Journal of Biological Chemistry, 2001 Chondroadherin is a cell binding, leucine-rich repeat protein found in the territorial matrix of articular cartilage. Several members of the leucine-rich repeat protein family present in the extracellular matrix of e.g. cartilage have been shown to interact with collagen and influence collagen fibrillogenesis.
B, Mansson +4 more
openaire +2 more sources
Marine Drugs, 2019 The composition and properties of collagen in teleost (bony fish) cartilage have never been studied. In this study, we aimed to identify and characterise all collagen species in the nasal cartilage of hoki (Macruronus novaezelandiae).
Mathew H. Cumming +2 more
doaj +1 more source
Collagen type II: From biosynthesis to advanced biomaterials for cartilage engineering
Biomaterials and Biosystems, 2021 Collagen type II is the major constituent of cartilage tissue. Yet, cartilage engineering approaches are primarily based on collagen type I devices that are associated with suboptimal functional therapeutic outcomes. Herein, we briefly describe cartilage'
Z Wu +3 more
doaj +1 more source
Arthritis Research & Therapy, 2021 Background Osteoarthritis (OA) is a disease of the whole joint, with articular cartilage breakdown as a major characteristic. Inflammatory mediators, proteases, and oxidants produced by chondrocytes are known to be responsible for driving cartilage ...
Anne Gigout +6 more
doaj +1 more source
A COL2A1 Mutation in Achondrogenesis Type II Results in the Replacement of Type II Collagen by Type I and III Collagens in Cartilage [PDF]
Journal of Biological Chemistry, 1995 An autosomal dominant mutation in the COL2A1 gene was identified in a fetus with achondrogenesis type II. A transition of G2853 to A in exon 41 produced a substitution of Gly769 by Ser within the triple helical domain of the alpha 1(II) chain of type II collagen, interrupting the mandatory Gly-X-Y triplet sequence required for the normal formation of ...
Chan, D +4 more
openaire +4 more sources
Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2020 Cell-based therapies such as Scaffold, stem cells, and secretome, are one of the alternatives to enhance the regeneration of hyaline-like cartilage in cases of cartilage defects.
Adrianto Prasetyo Perbowo +4 more
doaj +1 more source
Collagen-induced Arthritis: A Model for Murine Autoimmune Arthritis
Bio-Protocol, 2015 Collagen-induced arthritis (CIA) is a common autoimmune animal model used to study rheumatoid arthritis (RA). The development of CIA involves infiltration of macrophages and neutrophils into the joint, as well as T and B cell responses to type II ...
Kathryn Pietrosimone +3 more
doaj +1 more source
Hayati Journal of Biosciences, 2023 To extend plant benefits, three different concentrations of five Morinda citrifolia part was investigated on the collagen type II which is the primary collagen in human cartilage through the expression of the genes, COL2A1, COL-II and COLL2 regions in ...
Unchaleeporn Ameamsri +5 more
doaj +1 more source