Results 21 to 30 of about 286,259 (301)

A COL2A1 Mutation in Achondrogenesis Type II Results in the Replacement of Type II Collagen by Type I and III Collagens in Cartilage [PDF]

Journal of Biological Chemistry, 1995
An autosomal dominant mutation in the COL2A1 gene was identified in a fetus with achondrogenesis type II. A transition of G2853 to A in exon 41 produced a substitution of Gly769 by Ser within the triple helical domain of the alpha 1(II) chain of type II collagen, interrupting the mandatory Gly-X-Y triplet sequence required for the normal formation of ...
Chan, D, Cole, WG, Chow, CW, Mundlos, S, Bateman, JF   +4 more
openaire   +4 more sources

Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. [PDF]

, 2007
Epicutaneous immunization is a potential non-invasive technique for antigen-specific immune-modulation. Topical application of protein antigens to barrier-disrupted skin induces potent antigen-specific immunity with a strong Th2-bias.
Strobel, S, Strid, J, Callard, R, Marco Londei, Londei, M, Lee Aun Tan, Stephan Strobel, Robin Callard, Jessica Strid, Tan, LA   +9 more
core   +1 more source

Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]

, 2010
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H, Dzhambazov, Balik, Bockermann, Robert, Bettina Sehnert, Batsalova, Tsvetelina, Harald Burkhardt, Burkhardt, Harald, Robert Bockermann, Baecklund, Johan, Batsalova, T, Bockermann, R, Dzhambazov, B, Merky, Patrick, Baecklund, J, Bäcklund, Johan, Sehnert, B, Patrick Merky, Sehnert, Bettina, Balik Dzhambazov, Tsvetelina Batsalova, Lund University., Johan Backlund, Merky, P,, Bockermann, Robert,   +23 more
core   +1 more source

Collagen Type I and Type II Expression Evaluation on Cartilage Defect Regeneration Treated with Dwikora–Ferdiansyah–Lesmono–Purwati (DFLP) Scaffold Supplemented with Adipose–Derived Stem Cells (ASCs) or Secretome: An In-Vivo Study

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2020
Cell-based therapies such as Scaffold, stem cells, and secretome, are one of the alternatives to enhance the regeneration of hyaline-like cartilage in cases of cartilage defects.
Adrianto Prasetyo Perbowo, Dwikora Novembri Utomo, Lukas Widhiyanto, Primadenny Ariesa Airlangga, Purwati Purwati   +4 more
doaj   +1 more source

Immunohistochemical localization of collagen types I and VI in human skin wounds [PDF]

, 1996
A total of 74 human skin wounds were investigated and collagen types I and VI were localized in the wound area by immunohistochemistry. Collagen type I appeared in the form of ramifying string-like structures after approximately 5–6 days, but positive ...
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Wilske, J., Betz, P.   +5 more
core   +1 more source

Collagen-induced Arthritis: A Model for Murine Autoimmune Arthritis

Bio-Protocol, 2015
Collagen-induced arthritis (CIA) is a common autoimmune animal model used to study rheumatoid arthritis (RA). The development of CIA involves infiltration of macrophages and neutrophils into the joint, as well as T and B cell responses to type II ...
Kathryn Pietrosimone, Mengyao Jin, Brad Poston, Peng Liu   +3 more
doaj   +1 more source

Investigation of Morinda citrifolia Activity Related Collagen Type II Synthesis Through Gene Expression

Hayati Journal of Biosciences, 2023
To extend plant benefits, three different concentrations of five Morinda citrifolia part was investigated on the collagen type II which is the primary collagen in human cartilage through the expression of the genes, COL2A1, COL-II and COLL2 regions in ...
Unchaleeporn Ameamsri, Runglawan Sudmoon, Warin Wonok, Sanit Kaewdaungdee, Tawatchai Tanee, Arunrat Chaveerach   +5 more
doaj   +1 more source

Plasmid-Encoded Outer Membrane Protein YadA Mediates Specific Binding of Enteropathogenic Yersiniae to Various Types of Collagen [PDF]

, 1992
The plasmid-encoded outer membrane protein YadA of enteropathogenic yersiniae is associated with pathogenicity. Recently, collagen binding of YadA-positive yersiniae was reported without detailed characterization (L. Emödy, J. Heesemann, H. Wolf-Watz, M.
Emmerich, F., Burkhardt, H., Schulze-Koops, Hendrik, Heesemann, Jürgen, Mark, K. von der   +4 more
core   +1 more source

Categorization of collagen type I and II blend hydrogel using multipolarization SHG imaging with ResNet regression

Scientific Reports, 2023
Previously, the discrimination of collagen types I and II was successfully achieved using peptide pitch angle and anisotropic parameter methods. However, these methods require fitting polarization second harmonic generation (SHG) pixel-wise information ...
Anupama Nair, Chun-Yu Lin, Feng-Chun Hsu, Ta-Hsiang Wong, Shu-Chun Chuang, Yi-Shan Lin, Chung-Hwan Chen, Paul Campagnola, Chi-Hsiang Lien, Shean-Jen Chen   +9 more
doaj   +1 more source

Expression of collagen type I, II, X and Ki-67 in osteochondroma compared to human growth plate cartilage

European Journal of Histochemistry, 2010
In order to characterize the consequences for the process of endochondral ossification we performed an immunohistochemical study and compared the expression of collagen type I, II and X as markers of cartilage differentiation and Ki-67 as a marker of ...
K Huch, V Mordstein, J Stöve, AG Nerlich, H Arnholdt, G Delling, W Puhl, KP Günther, RE Brenner   +8 more
doaj   +1 more source