bioRxiv, 2021 Salmonella enterica serovar Typhimurium is a Gram-negative pathogen that uses two distinct type III secretion systems (T3SSs), termed Salmonella pathogenicity island (SPI)-1 and SPI-2, to deliver virulence factors into the host cell.
Nawar Naseer +4 more
semanticscholar +1 more source
Frontiers in Plant Science, 2013 Gram-negative plant pathogenic bacteria possess a type III secretion system (T3SS) to inject bacterial proteins, called type III effectors (T3Es), into host cells through a specialized syringe structure. T3Es are virulence factors that can suppress plant
David eLohou +8 more
doaj +1 more source
T3SS-dependent differential modulations of the jasmonic acid pathway in susceptible and resistant genotypes of Malus spp. challenged with Erwinia amylovora [PDF]
, 2012 Fire blight is a bacterial disease of Maloideae caused by Erwinia amylovora (Ea). This necrogenic enterobacterium uses a type III secretion system (T3SS) to inject type III effectors into the plant cells to cause disease on its susceptible hosts ...
J.F. Dat +6 more
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The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]
PLoS ONE, 2012 Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
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Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]
, 2014 Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T. +6 more
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The Shigella Type III Secretion System: An Overview from Top to Bottom
Microorganisms, 2021 Shigella comprises four species of human-restricted pathogens causing bacillary dysentery. While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion system (T3SS) is its primary virulence factor.
M. Muthuramalingam +3 more
semanticscholar +1 more source
Bacterial secretion systems contribute to rapid tissue decay in button mushroom soft rot disease
mBio, 2023 The soft rot pathogen Janthinobacterium agaricidamnosum causes devastating damage to button mushrooms (Agaricus bisporus), one of the most cultivated and commercially relevant mushrooms.
Philipp Wein +7 more
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Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB. [PDF]
, 2014 BackgroundBurkholderia pseudomallei is the causative agent of melioidosis, a potentially fatal disease endemic in Southeast Asia and Northern Australia.
Chen, Isabelle Gek Joo +9 more
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Modulation of the immune response by the Pseudomonas aeruginosa type-III secretion system
Frontiers in Cellular and Infection Microbiology, 2022 Pseudomonas aeruginosa is an opportunistic pathogen that can cause critical cellular damage and subvert the immune response to promote its survival. Among the numerous virulence factors of P.
Albane Jouault, A. M. Saliba, L. Touqui
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2018 Dozens of Gram negative pathogens use one or more type III secretion systems (T3SS) to disarm host defenses or occupy a beneficial niche during infection of a host organism. While the T3SS represents an attractive drug target and dozens of compounds with
Jessica M. Morgan +7 more
doaj +1 more source