Results 141 to 150 of about 259,068 (324)
Type VI Secretion Systems encoded by plasmids
, 2021 Trabajo presentado en la conferencia "Plasmids around the Globe", celebrada en modalidad virtual el 06 de mayo de 2021.
Quiñonero Coronel, María del Mar +1 more
openaire +1 more source
Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB. [PDF]
, 2014 BackgroundBurkholderia pseudomallei is the causative agent of melioidosis, a potentially fatal disease endemic in Southeast Asia and Northern Australia.
Chen, Isabelle Gek Joo +9 more
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
mSphereThe type VI secretion system (T6SS) serves as a crucial molecular weapon in interbacterial competition and significantly influences the adaptability of bacteria in their ecological niche.
Wanzhen Li +7 more
doaj +1 more source
Manipulating the type VI secretion system spike to shuttle passenger proteins.
PLoS ONE, 2020 The type VI secretion system (T6SS) is a contractile injection apparatus that translocates a spike loaded with various effectors directly into eukaryotic or prokaryotic target cells.
Sarah Wettstadt, Alain Filloux
doaj +1 more source
Extracellular matrix components are required to protect bacillus subtilis from pseudomonas invasion and co-colonization of plants [PDF]
, 2018 Plants are colonized by a vast variety of microbes. Among them, bacteria are the most predominant and are able to adapt to environmental changes and interact with other microorganisms using a wide array of molecules, metabolic plasticity and secretion ...
De-Vicente-Moreno, Antonio +3 more
core
Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition
MicrobiologyOpen, 2019 Burkholderia cenocepacia is an opportunistic bacterial pathogen that poses a significant threat to individuals with cystic fibrosis by provoking a strong inflammatory response within the lung.
Helena L. Spiewak +6 more
doaj +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroduction The type VI secretion system (T6SS) is a crucial virulence factor in the nosocomial pathogen Acinetobacter baumannii. However, its association with drug resistance is less well known. Notably, the roles that different T6SS components play in
Pu Li +13 more
semanticscholar +1 more source