Results 261 to 270 of about 25,500,999 (291)

A Novel Molecular Mechanism for Effector Protein Wrapping and Delivery by the Bacterial Type VI Secretion System

Paracuellos* P, Bexter* A, Patkowski JB, Omelchenko O, Macé K, Ilangovan A, Kelly SD, Whitney JC, Filloux A, Costa TR.   +9 more
europepmc   +1 more source

Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks

Tejada-Arranz A, Plack A, Antelo-Varela M, Kaczmarczyk A, Klotz A, Jenal U, Basler M.   +6 more
europepmc   +1 more source

Type VI Secretion System Effectors: Poisons With a Purpose [PDF]

Nature Reviews Microbiology, 2014
The type VI secretion system (T6SS) mediates interactions between a broad range of Gram-negative bacterial species. Recent studies have led to a substantial increase in the number of characterized T6SS effector proteins and a more complete and nuanced view of the adaptive importance of the system.
Alistair B Russell, Joseph D. Mougous, S Brook Peterson   +2 more
exaly   +3 more sources

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Bacterial Defense against the Type VI Secretion System

Trends in Microbiology, 2021
Bacteria have evolved systems dedicated to interbacterial competition. Here we highlight defenses utilized by Gram-negative cells against type VI secretion system (T6SS)-wielding competitors, including physical barriers, genetically encoded antidotes, and stress responses.
Sophie, Robitaille, Evan, Trus, Benjamin D, Ross   +2 more
openaire   +2 more sources

Type VI secretion system baseplate

Nature Microbiology, 2018
Bacteria employ a specialized weapon known as the type VI secretion system to defend themselves from competing organisms. A new study reveals the molecular architecture of the type VI secretion system and highlights conserved mechanistic similarities with contractile phage tails.
Alan R, Davidson, Karen L, Maxwell
openaire   +2 more sources

Bacterial strategies for immune systems — Role of the type VI secretion system

International Immunopharmacology, 2023
The process of host infection by bacteria is complicated. Bacterial infections strongly induce the host immune system, which necessitates a robust clearance of the infection. However, bacteria have over time developed strategies that enable their evasion of attacks by the host immune system.
Yurou Wang, Minmin Zeng, Lin Xia, Chinasa Valerie Olovo, Zhaoliang Su, Ying Zhang   +5 more
openaire   +2 more sources

The Type VI Secretion System and Associated Effector Proteins

Nature Reviews Microbiology
Bacteria have evolved a myriad of antibacterial weapons to engage in interbacterial conflicts. Among these, many Gram-negative bacteria use type VI secretion systems (T6SSs), which are contractile toxin delivery systems, to eliminate or suppress competitors in a contact-dependent manner.
Marek Basler, Joana Pereira, Danny Ward
exaly   +3 more sources

Identification of type VI secretion systems in Moritella viscosa

Veterinary Microbiology, 2012
The study describes the identification of type VI secretion systems (T6SSs) in Moritella viscosa, the aetiological agent of winter ulcer disease. Despite the availability of commercial vaccines, M. viscosa causes significant financial losses in salmonid farming.
Bryndis, Bjornsdottir, Erik, Hjerde, Birkir Th, Bragason, Thorunn, Gudmundsdottir, Nils P, Willassen, Bjarnheidur K, Gudmundsdottir   +5 more
openaire   +2 more sources

Expression, secretion and bactericidal activity of type VI secretion system in Vibrio anguillarum

Archives of Microbiology, 2016
The type VI secretion system (T6SS) was recently shown to modulate quorum sensing and the stress response in Vibrio anguillarum serotype O1 strain NB10. It is not known whether there is a functionally active T6SS in other serotypes of V. anguillarum. Here, homologues to T6SS cluster VtsEFGH and hemolysin-coregulated protein (Hcp)-encoding genes were ...
Lei, Tang, Shu, Yue, Gui-Yang, Li, Jie, Li, Xiao-Ran, Wang, Shu-Fang, Li, Zhao-Lan, Mo   +6 more
openaire   +2 more sources