Results 121 to 130 of about 54,266 (256)

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

The Pineal Gland Is Required for Optimal Nighttime Immunity to Bacterial Infection in Larval Zebrafish

Journal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT The immune response to bacterial infection demonstrates circadian rhythmicity, with heightened antibacterial immunity often observed during the daytime. This circadian‐gated immune response is believed to have evolved to synchronize peak antibacterial immunity with the increased threat of infection when active.
Gabriel Anasarias‐Dumo, Yevetta Y. Xiang, David Cumin, James F. Cheeseman, Guy R. Warman, Jonathan W. Astin, Christopher J. Hall   +6 more
wiley   +1 more source

Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles

Drug Design, Development and Therapy, 2015
Hwi Young Yun,1 Do Hyun Kim,1 Sujin Son,1 Sultan Ullah,1 Seong Jin Kim,1 Yeon-Jeong Kim,2 Jin-Wook Yoo,1 Yunjin Jung,1 Pusoon Chun,2 Hyung Ryong Moon1 1College of Pharmacy, Pusan National University, Busan, 2College of Pharmacy, Inje University, Gimhae,
Yun HY, Kim DH, Son S, Ullah S, Kim SJ, Kim YJ, Yoo JW, Jung YJ, Chun P, Moon HR   +9 more
doaj  

Staurosporine Drives Non‐Canonical Melanocyte Maturation by Coupling β‐Catenin Signaling to Actin‐Dependent Dendrite Remodeling

Pigment Cell &Melanoma Research, Volume 39, Issue 5, September 2026.
Staurosporine drives non‐canonical melanocyte maturation through β‐catenin‐dependent actin remodeling. Functional maturation enhances dendrite architecture and melanogenic differentiation without inducing melanocyte proliferation, providing a biological framework for restoring functional melanocytes in acquired hypopigmentary disorders.
Kangning Xu, Lingli Yang, Sylvia Lai, Fei Yang, Yasutaka Kuroda, Daisuke Tsuruta, Ichiro Katayama   +6 more
wiley   +1 more source

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna, Alicia Zamarrón, Cristina García‐Muñoz, Juan‐Carlos Hernández‐Rodríguez, Henry W. Lim, Salvador González   +5 more
wiley   +1 more source

Evaluation of Novel Isatin–Schiff Base Derivatives: Monoamine Oxidase Inhibition and Antimicrobial Assessment

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Five novel series of isatin–Schiff base derivatives are synthesized and evaluated for neuroprotective and anti‐infective potential. The compounds demonstrate exceptional, reversible, and competitive monoamine oxidase inhibition, with chloro‐substitutions dictating isoform selectivity.
Marthinus J. Jooste, Stephanus J. Cloete, Anél Petzer, Jacobus P. Petzer, Theunis T. Cloete   +4 more
wiley   +1 more source

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven, Mehmet Karadayı, Mustafa Abdullah Yilmaz, Osman Tugay, Oguz Cakir   +4 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Demonstrating Vibrational Current Generation With a Self‐Assembled Bioelectret

Advanced Functional Materials, Volume 36, Issue 65, 13 August 2026.
Vacuum‐deposited films of the plant‐derived molecule, Baicalein, form a self‐assembled bioelectret exhibiting spontaneous orientation polarization and a giant surface potential. The films induce alternating current during the vibration of a movable electrode without charging treatments. Hydrocarbon protection enhances the air stability of the Baicalein
Kouki Akaike, Yukihiro Shimoi, Qingshuo Wei, Yutaro Ono, Satomi Hosono, Yoichi Yamada, Haruhisa Akiyama, Shunsuke Tanaka   +7 more
wiley   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, Volume 2, Issue 4, August 2026.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source