Results 131 to 140 of about 45,442 (272)

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

open access: yesAdvanced Science, Volume 13, Issue 59, 23 October 2026.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa   +11 more
wiley   +1 more source

Inhibition effects of Eucalyptus globules Labill. essential oil against tyrosinase

open access: yesScientific Reports
Essential oils derived from Eucalyptus globules Labill. (EGEOs) represent a significant class of bioactive metabolites with broad applications in medicinal and pharmaceutical industries. Despite their various biological activities, the potential of EGEOs
Hua Zhu, Xin Zhong
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi   +6 more
wiley   +1 more source

Identifying melanogenesis inhibitors from Cinnamomum subavenium with in vitro and in vivo screening systems by targeting the human tyrosinase

open access: yes, 2011
Tyrosinase is known to be the first two and rate-limiting enzyme in the synthesis of melanin pigments responsible for colouring skin, hair and eyes. Tyrosinase inhibition is one major strategy used to treat hyperpigmentation.
Wang, Hui-Min ;Chen, Chung-Yi ;Wen, Zhi-Hong
core  

Mutational analysis of the modulation of tyrosinase by tyrosinase-related proteins 1 and 2 in vitro

open access: yes
The albino (tyrosinase, Tyrc), brown (tyrosinase-related protein 1, Tyrp1b) and slaty (tyrosinase-related protein 2, tyrp2slt) loci are all involved in the regulation of melanogenesis. Phenotypes of inbred mice mutant at two or more of these loci are not
Sato, K.   +5 more
core   +1 more source

Computational and biochemical evidence reveal cuminaldehyde as a potent tyrosinase inhibitor

open access: yesDiscover Chemistry
Inhibition of enzymes has been a major drug target for curing diseases. Xanthine oxidase is involved in the production of uric acid. The enzyme has elevated levels of activity in various diseases like gout, cardiovascular diseases etc.
Taranga Jyoti Baruah   +7 more
doaj   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella   +2 more
wiley   +1 more source

Inhibitory effect of the 50% ethanol extract of Solanum lyratum Thunb. on tyrosinase activity

open access: yes, 2009
[[abstract]]This study aimed to evaluate the inhibition properties of 50% ethanol extract from Solanum lyratum Thunb. (SLEE) toward the activity of tyrosinase.
Ming-Hsiung Chiu
core  

Phytochemical Characterization and Biological Activity of Stachys pinardii Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ultrasound‐assisted methanol and aqueous extracts of Stachys pinardii are comparatively evaluated for phytochemical composition and biological activities. Solvent polarity markedly influences phenolic profiles and bioactivity. Although the methanolic extract contains higher total phenolics, the aqueous extract exhibits superior antioxidant and enzyme ...
Zeyneb Karakus   +2 more
wiley   +1 more source

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