Results 141 to 150 of about 22,420 (243)

The phenological growth stages, heat unit requirement and anti‐tyrosinase activity of Greyia radlkoferi Szyszyl

open access: yesAnnals of Applied Biology, Volume 188, Issue 2, Page 549-560, March 2026.
Phenological growth stages of Greyia radlkoferi: The phenological growth stages of Greyia radlkoferi were monitored for a period of 3 years from 2018, 2019 and 2020. The flower budding, bud burst, flowering, fading, fruiting, seeding, leaf senescence and vegetative stage were recorded. The tyrosinase inhibitory activity of G.
Joseph Malele   +3 more
wiley   +1 more source

A model for de novo pigmentation of amelanotic retinal pigment epithelial cells

open access: yesActa Ophthalmologica, Volume 104, Issue 2, Page 212-224, March 2026.
Abstract Purpose Retinal Pigment Epithelial (RPE) cells perform critical functions in the visual cycle. Their melanin pigmentation, which is organized into specialized compartments – melanosomes, is highly critical for proper vision. A chemical method to induce pigmentation in a non‐pigmented model of ARPE‐19 cells was applied using L‐DOPA as a ...
Santosh Gupta   +10 more
wiley   +1 more source

Discovery of bis-thiourea derivatives as potent tyrosinase inhibitors: combined experimental and computational study

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry
Tyrosinase, a key enzyme in melanin synthesis, serves as a primary target for developing depigmenting agents. The search for novel tyrosinase inhibitors is needed due to the adverse effects of current inhibitors.
Sahachai Sabuakham   +6 more
doaj   +1 more source

Development of Optical Biosensor to Determine Benzoic Acid Concentration Based on Its Inhibitive Effect on Tyrosinase Enzyme [PDF]

open access: yes, 2010
An optical biosensor using phenol biosensor for the determination of benzoic acid based on inhibitive effect of benzoic acid on tyrosinase enzyme has been developed in this study.
Hamzah, Hairul Hisham
core  

Cannabidiol-Based Thiosemicarbazones: A Preliminary Study Evaluating Their Anti-Tyrosinase Properties

open access: yesMolecules
Cannabidiol (CBD), a non-psychoactive cannabinoid, has attracted significant research interest due to its antioxidant, anti-inflammatory, and neuroprotective properties.
Eliav Peretz, Noa Ashkenazi, Sanaa Musa
doaj   +1 more source

Inhibitory Effects of Grape Stem Extracts From Douro Varieties on Skin‐Aging Enzymes: A Sustainable Source of Cosmeceutical Agents

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Grape stems are a major by‐product of the winemaking process and remain largely underexploited despite their richness in bioactive phenolic compounds, representing an opportunity for sustainable valorization within a circular economy framework.
Maria Garcia‐Marti   +4 more
wiley   +1 more source

Exploring the Effectiveness, Tolerability, and Safety of the Adjunctive Use of Microneedling With Tranexamic Acid in the Treatment of Melasma

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Melasma is a chronic pigment disorder associated with significant psychosocial burden. The gold standard triple combination cream is effective but limited by relapse and adverse effects. Tranexamic acid (TXA) and microneedling have independently shown promise in the treatment of melasma, and their combined use may provide enhanced ...
Sharon Dhaliwal   +2 more
wiley   +1 more source

Melanin Metabolism: A Novel Oxidative Degradation Mechanism and Regulation by Hydrolyzed Conchiolin Protein

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Most pharmacological depigmenting agents and cosmetic skin‐brightening products achieve their effects by suppressing melanogenesis. However, the fate of melanin after melanosome transfer to keratinocytes—and the mechanisms governing its intracellular clearance—remains insufficiently explored.
Xinyi Zhao   +3 more
wiley   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

open access: yesPhotochemistry and Photobiology, Volume 102, Issue 2, Page 370-399, March/April 2026.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima   +6 more
wiley   +1 more source

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