Results 131 to 140 of about 22,637 (249)

Pengaruh Konsentrasi Natrium Alginat terhadap Gel Ekstrak Daun Teh Hijau (Camellia Sinensis L.) sebagai Inhibitor Tirosinase [PDF]

open access: yes, 2017
Daun teh hijau (Camellia sinensis L.) merupakan salah satu tanaman yang mengandung senyawa-senyawa polifenol seperti katekin dan galokatekin galat yang dapat digunakan sebagai inhibitor tirosinase.
Radjab, N. S. (Naniek)   +2 more
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The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, Volume 20, Issue 5, Page 1185-1201, May 2026.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

open access: yesBMC Chemistry
Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation.
Mohammad Azimi   +4 more
doaj   +1 more source

Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors

open access: yesFrontiers in Pharmacology
Tyrosinase (TYR) inhibitors are very significant as they inhibit enzyme tyrosinase activity, and its inhibition is vital for skin care, anticancer medication, and antibrowning of fruits and vegetables.
Ifraz Ahmad   +7 more
doaj   +1 more source

Skin Hyperpigmentation: An Under‐Recognized Dermatological Clue to Vitamin B12 Deficiency

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Hyperpigmentation over the dorsal aspect of both hands, prominently involving the knuckles. ABSTRACT Cutaneous hyperpigmentation, an overlooked manifestation, can be an early sign of vitamin B12 deficiency. This case highlights symmetric pigmentation on the dorsum of hands and palms in a long‐term vegetarian.
Mahesh Mathur   +5 more
wiley   +1 more source

TLC-Bioautographic Evaluation of Anti-tyrosinase and Anti-cholinesterase Potentials of Sandalwood Oil

open access: yesNatural Product Communications, 2013
Sandalwood oil, rich in sesquiterpenoid alcohols, has been used in traditional medicinal systems as a relaxant and coolant. Besides, sandalwood oil is used as an ingredient in numerous skin fairness enhancing cosmetics.
Biswapriya B. Misra, Satyahari Dey
doaj   +1 more source

Nanobiocatalysts: Potential Applications in Biofuel Production and Biotransformation

open access: yesCarbon Neutralization, Volume 5, Issue 3, May 2026.
The application of nanobiocatalysts in the field of biofuel production and the biotransformation of substrate were reviewed. Further, the possible research gaps in the field of biofuel and value‐added compound production and a possible way to enhance the application of nanobiocatalyst in future development are highlighted.
Preethi Muthu   +4 more
wiley   +1 more source

The research on tyrosinase inhibition and biological activity of cinnamaldehyde and its derivatives [PDF]

open access: yes, 2016
酪氨酸酶(EC1.14.18.1)是一种含铜的氧化还原酶,广泛分布于微生物,动物,植物和人体中,是生物体生命活动的关键酶。若人体中酪氨酸酶异常表达能引起雀斑和黑色素沉积等皮肤病,且其在昆虫的蜕皮及果蔬褐变中起了关键的作用,因此酪氨酸酶抑制剂的研究引起了广泛的关注。肉桂醛主要存在于天然樟科植物桂皮中,在农业、医药上具有重要的作用。 本文首先以蘑菇酪氨酸酶为对象,研究了肉桂醛及其α位C上取代的三种衍生物:α-溴代肉桂醛、α-氯代肉桂醛和α-甲基肉桂醛对酶的抑制作用,结果表明四者抑制50%单酚酶活性的浓度 ...
崔沂
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