Results 131 to 140 of about 568,389 (237)

Isolation and identification of actinomycetes F-97 producing tyrosinase inhibitor

open access: yes, 2009
In order to obtain a non-toxic and more active and stable microorganism-produced tyrosinase inhibitor, we isolated actinomycetes F-97, a producer of tyrosinase inhibitor, from soil.
J O Kim   +4 more
core  

Anti‐Aging Potential of Callus Culture: Mechanisms, Efficacy and Future Trends

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Callus culture technology revolutionizes skin antiaging research, offering a sustainable and efficient method for producing bioactive compounds with potent geroprotective properties. This plant tissue and cell culture technique enables the controlled biosynthesis of beneficial phytochemicals while mitigating the variability and ...
Amir Mohammad Sharafi   +8 more
wiley   +1 more source

Efficacy and Side Effects of Green Tea Extract on Facial Skin Aging: A Systematic Review

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background There has been an increasing demand for natural cosmeceuticals that can be used for their anti‐aging effects. Green tea extract (GTE) is a powerful antioxidant making it a promising candidate for combating photodamage and skin aging.
Taryn Lubbers   +4 more
wiley   +1 more source

Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation

open access: yes, 2016
Md Al-Amin, Jiafu Cao, Muhammad Naeem, Hasanul Banna, Min-Soo Kim, Yunjin Jung, Hae Young Chung, Hyung Ryong Moon, Jin-Wook Yoo College of Pharmacy, Pusan National University, Busan, South Korea Abstract: Hyperpigmentation caused by melanin ...
Moon HR   +8 more
core  

The Pineal Gland Is Required for Optimal Nighttime Immunity to Bacterial Infection in Larval Zebrafish

open access: yesJournal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT The immune response to bacterial infection demonstrates circadian rhythmicity, with heightened antibacterial immunity often observed during the daytime. This circadian‐gated immune response is believed to have evolved to synchronize peak antibacterial immunity with the increased threat of infection when active.
Gabriel Anasarias‐Dumo   +6 more
wiley   +1 more source

Staurosporine Drives Non‐Canonical Melanocyte Maturation by Coupling β‐Catenin Signaling to Actin‐Dependent Dendrite Remodeling

open access: yesPigment Cell &Melanoma Research, Volume 39, Issue 5, September 2026.
Staurosporine drives non‐canonical melanocyte maturation through β‐catenin‐dependent actin remodeling. Functional maturation enhances dendrite architecture and melanogenic differentiation without inducing melanocyte proliferation, providing a biological framework for restoring functional melanocytes in acquired hypopigmentary disorders.
Kangning Xu   +6 more
wiley   +1 more source

Discovery of bis-thiourea derivatives as potent tyrosinase inhibitors: combined experimental and computational study

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry
Tyrosinase, a key enzyme in melanin synthesis, serves as a primary target for developing depigmenting agents. The search for novel tyrosinase inhibitors is needed due to the adverse effects of current inhibitors.
Sahachai Sabuakham   +6 more
doaj   +1 more source

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

open access: yesPhotodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna   +5 more
wiley   +1 more source

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