Results 121 to 130 of about 22,637 (249)

Synthesis, biological evaluation, molecular docking, MD simulation and DFT analysis of new 3-hydroxypyridine-4-one derivatives as anti-tyrosinase and antioxidant agents

Heliyon
In the present study, ten new substituted 3-hydroxypyridine-4-one derivatives were synthesized in a four-step method, and their chemical structures were confirmed using various spectroscopic techniques.
Sara Sadeghian, Fateme Zare, Mehdi Khoshneviszadeh, Arian Fathi Hafshejani, Farhang Salahshour, Ahmadreza Khodabakhshloo, Lotfollah Saghaie, Ghazal Goshtasbi, Zahra Sarikhani, Alireza Poustforoosh, Razieh Sabet, Hossein Sadeghpour   +11 more
doaj   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Tyrosine-like condensed derivatives as tyrosinase inhibitors

Journal of Pharmacy and Pharmacology, 2012
AbstractObjectivesWe report the pharmacological evaluation of a new series of 3-aminocoumarins differently substituted with hydroxyl groups, which have been synthesized because they include in their structures the tyrosine fragment (tyrosine-like compounds), with the aim of discovering structural features necessary for tyrosinase inhibitory activity ...
Matos M. J, Santana L, Uriarte E, SERRA, SILVIA, Corda M, Fadda M. B, ERA, BENEDETTA, FAIS, ANTONELLA   +7 more
openaire   +2 more sources

Potent inhibition of human tyrosinase inhibitor by verproside from the whole plant of Pseudolysimachion rotundum var. subintegrum. [PDF]

J Enzyme Inhib Med Chem, 2023
Jung S, Woo SY, Park MH, Kim DY, Lee SU, Oh SR, Kim MO, Lee J, Ryu HW.   +8 more
europepmc   +1 more source

Fermentation and Enzymatic Pre‐Treatments to Modulate Sensory Properties of Extruded Plant‐Based Meat Alternatives

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
Fermentation, enzymatic hydrolysis, and enzymatic crosslinking are emerging pre‐treatments to improve the sensory properties of extruded plant‐based meat alternatives. This review critically examines current literature to identify underlying mechanisms, benefits, and key research gaps associated with these pre‐treatments.
Ravinder Singh, Michel Aliani, Warren Blunt, Filiz Koksel   +3 more
wiley   +1 more source

Pemanfaatan Ekstrak Khamir Phaffia Rhodozyma Sebagai Sumber Karotenoid Pada Penghambatan Tirosinase [PDF]

, 2017
Ekstrak khamir Phaffia rhodozyma mengandung senyawa karotenoid berupa astaxhantin yang memiliki aktivitas sebagai penghambat tirosinase. Senyawa ini dapat menghambat tirosinase dalam mekanisme pembentukan melanin.
Rahardhian, M. R. (Muhammad), Wulandari, W. (Wulandari)   +1 more
core  

Skin Lightening Treatments: A Review on the Effect of Intravenous Glutathione in the Disease States of Women [PDF]

, 2020
The skin bleaching industry is a global business with a vast array of anti-melanogenic choices including glutathione. Glutathione is synthesized in vivo but has been used as a bodily supplement by medical personnel to aid in preventative medicine.
Mthombeni, Buhle
core   +1 more source

Kojic acid-derived tyrosinase inhibitors: synthesis and bioactivity

Pharmaceutical and Biomedical Research, 2015
Tyrosinase is a key enzyme for melanin biosynthesis, catalyzing the oxidation of L-tyrosine to L-dopaquinone. The tyrosinase inhibition is an effective approach to control hyperpigmentation in human skin and enzymatic browning in fruits and vegetables ...
Seyedeh Mahdieh Hashemi, Saeed Emami
doaj  

Investigation of phenyllactic acid as a potent tyrosinase inhibitor produced by probiotics. [PDF]

Curr Res Food Sci, 2023
Shin M, Truong VL, Lee M, Kim D, Kim MS, Cho H, Jung YH, Yang J, Jeong WS, Kim Y.   +9 more
europepmc   +1 more source

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source