Results 121 to 130 of about 568,389 (237)

Kojic acid-derived tyrosinase inhibitors: synthesis and bioactivity

Pharmaceutical and Biomedical Research, 2015
Tyrosinase is a key enzyme for melanin biosynthesis, catalyzing the oxidation of L-tyrosine to L-dopaquinone. The tyrosinase inhibition is an effective approach to control hyperpigmentation in human skin and enzymatic browning in fruits and vegetables ...
Seyedeh Mahdieh Hashemi, Saeed Emami
doaj  

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Antioxidant and tyrosinase inhibitor from Leucaena leucocephala

, 2013
The experimental design is divided into two parts: chemical analysis and bioactive assay. One antioxidant lupeol (4) and one inhibition of tyrosinase pheophorbide a methyl ester (7) were identified in Leucaena leucocephala.
Hsing-Tan Li;Syun-Wun Ruan;Jin-Cherng Huang;Hsin-Liang Chen;Chen, Chung-Yi
core  

Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

BMC Chemistry
Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation.
Mohammad Azimi, Zahra Najafi, Asrin Bahmani, Gholamabbas Chehardoli, Aida Iraji   +4 more
doaj   +1 more source

From Fish Scale Gelatin to Tyrosinase Inhibitor: A Novel Peptides Screening Approach Application. [PDF]

Front Nutr, 2022
Hu ZZ, Sha XM, Zhang L, Zha MJ, Tu ZC.
europepmc   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

Small, Volume 22, Issue 49, 1 September 2026.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

Purification and characteristics of tyrosinase inhibitor produced by actinomycetes F-97

, 2008
An actinomycetes F-97 producing tyrosinase inhibitor was isolated from soil samples. Isolation and purification of tyrosinase inhibitor produced by F-97 was performed as follows: IRC-120 (NH4+ type) column chromatography, silica gel column chromatography,
J O Kim, D H Yi, B H Bang, Moon Soo Rhee
core  

Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors

Frontiers in Pharmacology
Tyrosinase (TYR) inhibitors are very significant as they inhibit enzyme tyrosinase activity, and its inhibition is vital for skin care, anticancer medication, and antibrowning of fruits and vegetables.
Ifraz Ahmad, Warda Parveen, Shah Noor, Zahoor Udin, Amjad Ali, Ijaz Ali, Riaz Ullah, Hamid Ali   +7 more
doaj   +1 more source

Cephalosporin as Potent Urease and Tyrosinase Inhibitor: Exploration through Enzyme Inhibition, Kinetic Mechanism, and Molecular Docking Studies. [PDF]

Biomed Res Int, 2022
Alqahtani YS, Alyami BA, Alqarni AO, Mahnashi MH, Mahnashi MH, Ali A, Javed Q, Hassan M, Ehsan M.   +8 more
europepmc   +1 more source

Comprehensive Review on Green Transformation of Organic Waste Into Bioenergy Using Microbial Enzymes: Advances, Challenges, and Future Strategies

GCB Bioenergy, Volume 18, Issue 9, September 2026.
Microbial enzyme‐mediated biorefineries enable the sustainable conversion of organic waste into renewable bioenergy and value‐added products. Recent advances on enzymatic pretreatment, enzyme cocktails, and hybrid processing enhance biogas, bioethanol, and biodiesel production, along with supporting efficient waste valorization, circular bioeconomy ...
Divya Divakaran, Indran Suyambulingam, Ananth Selvan, Nadir Ayrilmis, P. Merlin Christy, M. Gomathi, P. Senthamaraikannan   +6 more
wiley   +1 more source