Results 121 to 130 of about 12,040 (235)

The Impact of Immunotherapy on Hair Repigmentation in Patients With Thoracic Tumors: A Clinical Observation Based on Trichoscopy

Thoracic Cancer, Volume 17, Issue 13, July 2026.
This prospective study quantitatively evaluates the phenomenon of hair repigmentation in patients with thoracic tumors undergoing immunotherapy. Using standardized trichoscopy and grayscale analysis, we observed a significant darkening of hair color following treatment with PD‐1/PD‐L1 inhibitors.
Sitong Jiang, Bo Li, Fan Yang, Haozhen Lv, Xin Nie, Hui Wang, Jianmin Chang, Lin Li   +7 more
wiley   +1 more source

Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

BMC Chemistry
Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation.
Mohammad Azimi, Zahra Najafi, Asrin Bahmani, Gholamabbas Chehardoli, Aida Iraji   +4 more
doaj   +1 more source

Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors

Frontiers in Pharmacology
Tyrosinase (TYR) inhibitors are very significant as they inhibit enzyme tyrosinase activity, and its inhibition is vital for skin care, anticancer medication, and antibrowning of fruits and vegetables.
Ifraz Ahmad, Warda Parveen, Shah Noor, Zahoor Udin, Amjad Ali, Ijaz Ali, Riaz Ullah, Hamid Ali   +7 more
doaj   +1 more source

Comparison of 1064‐nm Picosecond and Q‐Switched Neodymium‐Doped Yttrium Aluminum Garnet Lasers for Melasma in Asian Women: A Randomized Double‐Blind Split‐Face Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Melasma is a chronic, relapsing facial hyperpigmentation that remains challenging to treat in medium‐to‐dark phototypes. Aims To compare the efficacy, safety, tolerability, and recurrence of 1064‐nm picosecond neodymium‐doped yttrium aluminum garnet laser treatment versus 1064‐nm Q‐switched neodymium‐doped yttrium aluminum garnet ...
Ying Wu, Qixuan Wang, Jiayi Feng, Zehua Chen, Lvping Huang, Yongqiang Feng, Xiaojing Li   +6 more
wiley   +1 more source

1-(2,4-Dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane, a Novel Tyrosinase Inhibitor with Strong Depigmenting Effects

, 2008
A series of diarylpropane compounds was isolated by screening a plant extract library for inhibitors of mushroom tyrosinase. The most potent compound, 1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane (UP302: CAS# 869743-37-3), was found in
Minter, David, Ma, Wenwen, Zhao, Jifu, Abeysinghe, Padmapriya, Hong, Mei, Nesterov, Alexandre, Jia, Qi, Hertel, Carmen   +7 more
core   +1 more source

From Fish Scale Gelatin to Tyrosinase Inhibitor: A Novel Peptides Screening Approach Application. [PDF]

Front Nutr, 2022
Hu ZZ, Sha XM, Zhang L, Zha MJ, Tu ZC.
europepmc   +1 more source

TLC-Bioautographic Evaluation of Anti-tyrosinase and Anti-cholinesterase Potentials of Sandalwood Oil

Natural Product Communications, 2013
Sandalwood oil, rich in sesquiterpenoid alcohols, has been used in traditional medicinal systems as a relaxant and coolant. Besides, sandalwood oil is used as an ingredient in numerous skin fairness enhancing cosmetics.
Biswapriya B. Misra, Satyahari Dey
doaj   +1 more source

Advances in the Application of Chemical Peels in the Treatment of Pigmentary Skin Disorders

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Pigmentary disorders, including melasma, postinflammatory hyperpigmentation (PIH), solar lentigines, Riehl's melanosis, and periorbital hyperpigmentation, are common concerns in cosmetic dermatology, particularly in patients with skin of color.
Yuxin Li, Wenzhong Xiang
wiley   +1 more source

Cephalosporin as Potent Urease and Tyrosinase Inhibitor: Exploration through Enzyme Inhibition, Kinetic Mechanism, and Molecular Docking Studies. [PDF]

Biomed Res Int, 2022
Alqahtani YS, Alyami BA, Alqarni AO, Mahnashi MH, Mahnashi MH, Ali A, Javed Q, Hassan M, Ehsan M.   +8 more
europepmc   +1 more source

Efficacy and Tolerability of Topical Trifarotene in Managing Acne Vulgaris Among Malaysians: A Single Arm, Open Label, Observational Study

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Trifarotene is a new fourth‐generation topical retinoid that selectively binds to RAR‐γ receptors. However, the efficacy and safety data of trifarotene on Asians are lacking. Thus, we evaluated its real‐world efficacy and tolerability among Malaysians.
Jun Hui Goh, Tatt Quan Tan, Wen Chung Ho, Chi Fai Lee, Meroshini Sundaran, JiaXu An, Kang Nien How   +6 more
wiley   +1 more source