Results 141 to 150 of about 568,389 (237)

Cannabidiol-Based Thiosemicarbazones: A Preliminary Study Evaluating Their Anti-Tyrosinase Properties

Molecules
Cannabidiol (CBD), a non-psychoactive cannabinoid, has attracted significant research interest due to its antioxidant, anti-inflammatory, and neuroprotective properties.
Eliav Peretz, Noa Ashkenazi, Sanaa Musa
doaj   +1 more source

Evaluation of Novel Isatin–Schiff Base Derivatives: Monoamine Oxidase Inhibition and Antimicrobial Assessment

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Five novel series of isatin–Schiff base derivatives are synthesized and evaluated for neuroprotective and anti‐infective potential. The compounds demonstrate exceptional, reversible, and competitive monoamine oxidase inhibition, with chloro‐substitutions dictating isoform selectivity.
Marthinus J. Jooste, Stephanus J. Cloete, Anél Petzer, Jacobus P. Petzer, Theunis T. Cloete   +4 more
wiley   +1 more source

Tyrosinase-Mediated Oxidative Coupling of Tyrosine Tags on Peptides and Proteins

, 2019
We report a strategy for chemical protein modification by using tyrosinase enzymes to oxidize exposed tyrosine residues on protein N or C-termini. We explore the chemical space for coupling partners in this reaction and find combinations that can proceed
Alan Marmelstein (5803390), Daniel D. Brauer (5797553), Casey S. Mogilevsky (7466378), Johnathan Maza (5803382), Marco Lobba (7466247), Matthew Francis (5811119)   +5 more
core   +1 more source

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven, Mehmet Karadayı, Mustafa Abdullah Yilmaz, Osman Tugay, Oguz Cakir   +4 more
wiley   +1 more source

Development of chemometric-assisted supercritical fluid extraction of effective and natural tyrosinase inhibitor from Syzygium aqueum leaves [PDF]

Tyrosinase is a key enzyme in enzymatic browning, causing quality losses in food through the oxidation process. Thus, the discovery of an effective and natural tyrosinase inhibitor via green technology is of great interest to the global food market due ...
Zanariah, Abdullah, Nurul Husna, Zarudin, Mohammad Norazmi, Ahmad, Ahmad Sazali, Hamzah, Mohd Bijarimi, Mat Piah, Syamimi Sulfiza, Shamsuri, Anwar, Iqbal, Erna, Normaya   +7 more
core   +1 more source

Unsymmetrical Binding Modes of the HOPNO Inhibitor of Tyrosinase: From Model Complexes to the Enzyme

, 2013
International audienceThe deciphering of the binding mode of tyrosinase (Ty) inhibitors is essential to understand how to regulate the tyrosinase activity.
Luneau, Dominique, Serratrice G, Dubois, C., Serratrice, Guy, Luneau, D., Jamet, Hélène, Bubacco, L., Carrupt, Pierre-Alain, Baptiste B, Réglier, M., Hardré R, Jamet, H., Carrupt PA, Moreau, Yohann, Gellon, G., Serratrice, G., Nurisso A, Bochot, Constance, Jamet H., Dubois C, Belle C, Bubacco, Luigi, Constance, Bochot, Gellon, Gisèle, Réglier M, Bochot C, Favre, Anne Elisabeth, Baptiste, B., Hardré, R., Belle, Catherine, Belle, C., Favre, Elisabeth, Hardré, Renaud, Réglier, Marius, Nurisso, Alessandra, Bochot, C., Moreau Y, Dubois, carole, Moreau, Y., Luneau D, Favre E, Gellon G, Baptiste, Benoît   +42 more
core   +1 more source

The study on the tyrosinase inhibitor produced by burkholderia cepacia TKU026 using squid pen as thesole carbon/nitrogen sources

, 2010
碩士本研究係以水產廢棄物為主要碳/氮源，經微生物發酵後其可生產酪胺酸酶抑制劑，並探討其較適培養條件為研究目的。使用菌株為Burkholderia cepacia TKU026，源自台灣北部土壤。 以50mL液態培養基含1％ 烏賊軟骨粉（squid pen powder；SPP）、0.1％ K2HPO4及0.05％ MgSO4．7H2O於250mL三角錐瓶，置放37℃、150rpm震盪培養三天可得較高酪胺酸酶抑制劑活性（5000U/mL ...
許家豪; Hsu, Chia-hao
core  

Nitrophenylpiperazine derivatives as novel tyrosinase inhibitors: design, synthesis, and in silico evaluations

BMC Chemistry
A novel series of 4-nitrophenylpiperazine derivatives (4a–m) was designed and synthesized as potential tyrosinase inhibitors. Comprehensive characterization using 1H-NMR, 13C-NMR, CNH, and IR techniques was performed for all target compounds ...
Mehdi Asadi, Fahime Fayazi, Aida Iraji, Reyhaneh Sabourian, Homa Azizian, Mannan Hajimahmoodi, Bagher Larijani, Mohammad Mahdavi, Massoud Amanlou   +8 more
doaj   +1 more source

Tyrosinase inhibition kinetics of anisic acid [PDF]

, 2003
Anisic acid (p-methoxybenzoic acid) was characterized as a tyrosinase inhibitor from aniseed, a common food spice. It inhibited the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by tyrosinase with an IC(50) of 0.60 mm.
陈清西, Cespedes, C. L., Calderon, J. S., Nihei, K., Kubo, I., Chen, Q. X.   +5 more
core  

Chicken Egg White-Advancing from Food to Skin Health Therapy: Optimization of Hydrolysis Condition and Identification of Tyrosinase Inhibitor Peptides. [PDF]

Foods, 2020
Yap PG, Gan CY.
europepmc   +1 more source