Results 101 to 110 of about 12,040 (235)

DOCKING OF TYROSINASE CICLOARTANE INHIBITORS

Vitae, 2009
Berenjenol (21:24-epoxy-24-methyl-cicloartane) isolated from leaves of Oxandra cf. xylopioides (Annonaceae), and its synthetic derivatives Berenjenol-3-acetate and 3-Oxoberenjenol are tyrosinase inhibitors (EC 1.14.18.1). These compounds are triterpenoids type cycloartanes, whose structure-activity relationship has been studied on similar compounds ...
Pablo A. GUTIÉRREZ, Benjamín A. ROJANO
openaire   +2 more sources

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven, Mehmet Karadayı, Mustafa Abdullah Yilmaz, Osman Tugay, Oguz Cakir   +4 more
wiley   +1 more source

Investigation of Phenolic Compounds by RP-HPLC and Antioxidant, Antimicrobial, Tyrosinase Inhibitor Activities of Clinopodium vulgare L. subsp. vulgare Extract

, 2018
Clinopodium vulgare L. subsp. vulgare, Clinopodium cinsine ve Lamiaceae familyasına mensup çok yıllık aromatik otsu bir bitkidir. Bu cins bitkiler sıklıkla geleneksel tedavide kullanılmaktadır.
Aliyazıcıoğlu, Rezzan, Nuriye Korkmaz, Şengül Alpay Karaoğlu, Rezzan Aliyazıcıoğlu, Akkaya, Şeyda, Sıla Özlem Şener, Korkmaz, Nuriye, Şener, Sıla Özlem, Ufuk Özgen, Badem, Merve, Özgen, Ufuk, Karaoğlu, Şengül Alpay, Şeyda Akkaya   +12 more
core   +1 more source

Polyphenol oxidase depletion in Nicotiana benthamiana enhances recombinant protein purification and preserves native protein integrity

New Phytologist, Volume 251, Issue 3, Page 1283-1293, August 2026.
Polyphenol oxidases (PPOs) depletion preserves endogenous proteins at their predicted molecular weights and enhances detectable enzymatic activities. (a) Less RbcL crosslinking in ppo mutant of Nicotiana benthamiana. Leaf extracts were incubated for 1 h, separated on protein gels, stained with Coomassie or analyzed by Western blot with the anti‐RbcL ...
Kaijie Zheng, Farnusch Kaschani, Emma C. Watts, Markus Kaiser, Renier A. L. van der Hoorn   +4 more
wiley   +1 more source

Caffeic acid-MHIRL derived Peptide Conjugates as Antioxidant and Tyrosinase Inhibitor [PDF]

, 2016
학위논문 (석사)-- 서울대학교 대학원 : 화학생물공학부, 2016. 2. 이윤식.인간의 몸 속에서 산화반응을 통해 생성되는 과량의 활성산소는 다양한 질병과 노화를 일으키는 중요한 원인이기에 이를 방지하는 항산화제에 대한 연구가 중요하다. 또, 인간의 피부와 눈의 색을 결정하는 멜라닌의 과량 생성은 피부질환과 신경변성과 관련된 질환이 생기므로 이에 관여하는 효소인 타이로시나제의 억제제가 개발되고 있다.
이은진
core  

红景天水提液对酪氨酸酶抑制效果的初步研究

四川大学学报. 自然科学版, 2006
To discuss the inhibiting mechanism of water extraxt solution from Rhodiola on theTyrosinase activity.Tyrosinase inhibiting rate is determined and Lineweaver-Burk curve is made by determining the tyrosinase activity before and after drug（water extract ...
龚静, 张飞伟, 韩锐, 吕雪艳, 王丽丽, 伊芬芬, 乔代蓉   +6 more
doaj  

Ligand‐Level Chemical Activation: Coordination with Benefits

European Journal of Inorganic Chemistry, Volume 29, Issue 19, 2 July 2026.
While often perceived as a liability, ligand‐based reactivity in carefully designed settings becomes a powerful synthetic tool. The key to streamlined processes overriding classical ionic reactivity is the selective electron redistribution induced by metal coordination. This enables storage of electrons and protons or incorporation of functional groups
Oscar Charpentier, Agnideep Das, Marine Desage‐El Murr   +2 more
wiley   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, Volume 13, Issue 39, 13 July 2026.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Combination of small molecule microarray and confocal microscopy techniques for live cell staining fluorescent dye discovery

, 2013
Discovering new fluorochromes is significantly advanced by high-throughput screening (HTS) methods. In the present study a combination of small molecule microarray (SMM) prescreening and confocal laser scanning microscopy (CLSM) was developed in order to
Bhavyashree Suresh, Ferhan Ayaydin, Bokros, Attila, Eszter Molnár, Peksel, Begüm, Ágnes Medgyesi, Liliána Fehér, Pradeep Kumar Reddy Cingaram, Puskás, László G., Soujanya Kuntam, Attila Bokros, Begüm Peksel, Gabriella Fábián, Molnár, Eszter, László G. Puskás, Kuntam, Soujanya, Liliána Z. Fehér, Fábián, Gabriella, László Puskás, Cingaram, Pradeep Kumar Reddy, Pradeep Cingaram   +20 more
core   +1 more source

Inhibitory effect of Fucofuroeckol-A from Eisenia bicyclis on tyrosinase activity and melanin biosynthesis in murine melanoma B16F10 cells

Fisheries and Aquatic Sciences, 2018
Background The aim of this study was to investigate the in vitro inhibitory effects of Fucofuroeckol-A isolated from Eisenia bicyclis against tyrosinase activity and 3-isobutyl-1-methylxanthine (IBMX)-induced melanin biosynthesis in B16F10 melanoma cells.
Kil Bo Shim, Na Young Yoon
doaj   +1 more source