Results 91 to 100 of about 568,389 (237)

Tyrosinase inhibitory activity of supernatant and semi-purified extracts from squid pen fermented with Burkholderia cepacia TKU025

open access: yes, 2014
Reports of tyrosinase inhibitors from microorganisms are rare. The tyrosinase inhibitory activity was found from the culture supernatant of Burkholderia cepacia TKU025 with 1 % squid pen as the sole carbon/nitrogen source.
Liang, Tzu-Wen, Wang, San-Lang
core   +1 more source

Tyrosinase Inhibitory Activity of Methanolic Extract and Fractions from Green Seaweed Ulva lactuca

open access: yesSqualen
Ulva lactuca, a widely available green seaweed, has demonstrated promising bioactivity as a tyrosinase inhibitor. This study aimed to evaluate the tyrosinase inhibitory activity of U. lactuca extracts and identify the active compounds responsible.
Mohamad Gazali   +7 more
doaj   +1 more source

Tyrosinase Inhibitors from Crude Drugs.

open access: yesBiological and Pharmaceutical Bulletin, 1994
Various crude drugs were examined for their tyrosinase inhibitory activity. Marked activity was observed in Chouji and Yakuchi extracts and the active substances in these extracts were identified as eugenol and yakuchinone A, respectively. Other vanillyl compounds such as ferulic acid, curcumin and yakuchinone B also had higher activities than eugenol ...
SHIROTA, Sachiko   +4 more
openaire   +3 more sources

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang   +7 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Elektrode Komposit Zeolit sebagai Biosensor Berbasis Tirosinase

open access: yes, 2014
Tyrosinase is a copper-containing oxidase, which catalyzes the first 2 steps in mammalian melanogenesis and responsible for enzymatic browning reactions.
Yunita, Maryani
core  

Peptide and peptidomimetic tyrosinase inhibitors

open access: yes
Melanin, which is produced by melanocytes and spread over keratinocytes, is responsible for human skin browning. There are several processes involved in melanogenesis, mostly prompted by enzymatic activities. Tyrosinase (TYR), a copper containing metalloenzyme, is considered the main actor in melanin production, as it catalyzes two crucial steps that ...
Errante, Fosca   +4 more
openaire   +3 more sources

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

open access: yesInternational Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster   +12 more
wiley   +1 more source

In Vitro In Silico Screening Strategy and Mechanism of Novel Tyrosinase Inhibitory Peptides from Nacre of Hyriopsis cumingii

open access: yesMarine Drugs
For thousands of years, pearl and nacre powders have been important traditional Chinese medicines known for their skin whitening effects. To prepare the enzymatic hydrolysates of Hyriopsis cumingii nacre powder (NP-HCH), complex enzymatic hydrolysis by ...
Haisheng Lin   +9 more
doaj   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

open access: yesInternational Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad   +2 more
wiley   +1 more source

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