Results 81 to 90 of about 706,934 (223)

Tyrosinase Inhibitors from Crude Drugs.

Biological and Pharmaceutical Bulletin, 1994
Various crude drugs were examined for their tyrosinase inhibitory activity. Marked activity was observed in Chouji and Yakuchi extracts and the active substances in these extracts were identified as eugenol and yakuchinone A, respectively. Other vanillyl compounds such as ferulic acid, curcumin and yakuchinone B also had higher activities than eugenol ...
SHIROTA, Sachiko, MIYAZAKI, Kouji, AIYAMA, Ritsuo, ICHIOKA, Minoru, YOKOKURA, Teruo   +4 more
openaire   +3 more sources

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Tyrosinase Inhibitory Activity of Methanolic Extract and Fractions from Green Seaweed Ulva lactuca

Squalen
Ulva lactuca, a widely available green seaweed, has demonstrated promising bioactivity as a tyrosinase inhibitor. This study aimed to evaluate the tyrosinase inhibitory activity of U. lactuca extracts and identify the active compounds responsible.
Mohamad Gazali, Fazidatul Lu’luil Maknun, Amir Husni, Nurjanah Nurjanah, Muhammad Nursid, Uswatun Hasanah, Zuriat Zuriat, Rina Syafitri   +7 more
doaj   +1 more source

Tyrosinase Inhibitor Activity of Coumarin-Resveratrol Hybrids

Molecules, 2009
In the present work we report on the contribution of the coumarin moiety to tyrosinase inhibition. Coumarin-resveratrol hybrids 1-8 have been resynthesized to investigate the structure-activity relationships and the IC50 values of these compounds were ...
Giovanna Delogu, Lourdes Santana, Carmen Picciau, Gianni Podda, Elias Quezada q, Maria Joao Matos, M. Benedetta Fadda, Benedetta Era, Marcella Corda, Antonella Fais   +9 more
doaj   +1 more source

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

International Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster, T. Rogers, C. Vendruscolo, D. Roggenkamp, W. G. Philipp‐Dormston, F. Al‐Niaimi, S. Roussel, N. Kiss, H. Malik, D. Grozeva, K. S. Berger, C. Rauscher, L. Kolbe   +12 more
wiley   +1 more source

Tyrosinase inhibition kinetics of anisic acid [PDF]

, 2003
Anisic acid (p-methoxybenzoic acid) was characterized as a tyrosinase inhibitor from aniseed, a common food spice. It inhibited the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by tyrosinase with an IC(50) of 0.60 mm.
陈清西, Cespedes, C. L., Calderon, J. S., Nihei, K., Kubo, I., Chen, Q. X.   +5 more
core  

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

International Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar, Sunil Dogra, Surabhi Sinha, Keshavamurthy Vinay, Indrashis Podder, Anupam Das, Bhavesh Swarnkar, B. S. Chandrashekar, Hitaishi Mehta, Madhuri Agarwal, Muthu Sendhil Kumaran, Sonali Langar, Seemal R. Desai   +12 more
wiley   +1 more source

Cosmetic Dermatology in Pregnancy and Lactation: A Risk–Benefit Framework for Clinical Practice

International Journal of Dermatology, EarlyView.
Summary of the safety profile of common cosmetic dermatology interventions during pregnancy and lactation. ABSTRACT Cosmetic dermatologic products and procedures are increasingly utilized by women of reproductive age, including those who are pregnant or lactating.
Timea Kovacs, Umer Nadir, Michael Goldenberg, Thomas E. Rohrer, Deirdre Hooper, George M. Jeha, Stanislav N. Tolkachjov   +6 more
wiley   +1 more source

Inhibitory effect of the 50% ethanol extract of Solanum lyratum Thunb. on tyrosinase activity

, 2009
[[abstract]]This study aimed to evaluate the inhibition properties of 50% ethanol extract from Solanum lyratum Thunb. (SLEE) toward the activity of tyrosinase.
Ming-Hsiung Chiu
core