Results 81 to 90 of about 12,040 (235)

Design, synthesis and biological evaluation of novel kojic acid triazole hybrids as tyrosinase inhibitors and antibrowning agents

Scientific Reports
In this study, two series of kojic acid triazole hybrids, namely 6a–6p and 13a–13t, were designed and synthesized. Subsequently, their biological activities including anti-tyrosinase, antioxidant, and as anti-browning effects were investigated.
Dan Liu, Junyuan Tang, Sheng Tao, Dahan Wang, Jinbing Liu   +4 more
doaj   +1 more source

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

International Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang, Hong Zhang, Chengming Zhang, Wencai Jiang, Luonan Chen, Yimei Tan, Ying Zou, Xuelan Gu   +7 more
wiley   +1 more source

Peptide and peptidomimetic tyrosinase inhibitors

Melanin, which is produced by melanocytes and spread over keratinocytes, is responsible for human skin browning. There are several processes involved in melanogenesis, mostly prompted by enzymatic activities. Tyrosinase (TYR), a copper containing metalloenzyme, is considered the main actor in melanin production, as it catalyzes two crucial steps that ...
Errante, Fosca, Sforzi, Lucrezia, Supuran, Claudiu T., Papini, Anna Maria, Rovero, Paolo   +4 more
openaire   +3 more sources

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Antioxidant, antimicrobial, and tyrosinase inhibitor activities in the aerial parts of onobrychis oxyodonta [PDF]

, 2017
Amaç: Dünyada geniş bir alana yayılmış olan Onobrychis türleri, yüksek antioksidan aktiviteye sahip fenolik madde içeriğinden dolayı tıbbi aromatik bitkiler arasında önemli bir yere sahiptir.
Korkmaz, Nuriye, Şener, Sıla Özlem, Aliyazıcıoğlu, Rezzan, Badem, Merve, Akkaya, Şeyda, Özgen, Ufuk, Karaoğlu, Şengül Alpay   +6 more
core  

The hypopigmentary action of KI-063 (a new tyrosinase inhibitor) combined with terrein

, 2008
Resorcinol derivatives are known to inhibit melanin synthesis. In this study, resorcinol derivatives were synthesized and screened for their activity on melanogenesis.
S H Park, Ick Dong Yoo, K C Park, D S Kim, H K Lee, J B Kwang, S B Kwon, Sangku Lee, J I Na, In Ja Ryoo   +9 more
core   +1 more source

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

International Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster, T. Rogers, C. Vendruscolo, D. Roggenkamp, W. G. Philipp‐Dormston, F. Al‐Niaimi, S. Roussel, N. Kiss, H. Malik, D. Grozeva, K. S. Berger, C. Rauscher, L. Kolbe   +12 more
wiley   +1 more source

Isolation and identification of actinomycetes F-97 producing tyrosinase inhibitor

, 2009
In order to obtain a non-toxic and more active and stable microorganism-produced tyrosinase inhibitor, we isolated actinomycetes F-97, a producer of tyrosinase inhibitor, from soil.
J O Kim, D H Yi, B H Bang, G P Kim, Moon Soo Rhee   +4 more
core  

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

International Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad, Nicole E. Chin, Raj Chovatiya   +2 more
wiley   +1 more source

Potency of Jack Fruit Leaves as Tyrosinase Inhibitor

, 2016
The aim of this study is to screen whitening agent potency from Jack fruit leaves compared between 96% ethanol extract from young Jack fruit leaves (green to white) and mature Jack fruit leaves (dark green).
Gunawan, Hendra, P. Priosoeryanto, Bambang, Wientarsih, Ietje, Rayendra, Raendi   +3 more
core   +1 more source