Results 71 to 80 of about 568,389 (237)

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Hydroxylated biphenyls as tyrosinase inhibitor: A spectrophotometric and electrochemical study

, 2017
A small collection of C2-symmetry hydroxylated biphenyls was prepared by straightforward methods and the capability to act as inhibitors of tyrosinase has been evaluated by both spectrophotometric and electrochemical assays.
Ruzza, Paolo, SERRA, Pier Andrea, Fabbri, Davide, ROCCHITTA, Gaia Giovanna Maria, Dettori, Maria Antonietta, Delogu, Giovanna   +5 more
core   +2 more sources

Inhibition effects of Eucalyptus globules Labill. essential oil against tyrosinase

Scientific Reports
Essential oils derived from Eucalyptus globules Labill. (EGEOs) represent a significant class of bioactive metabolites with broad applications in medicinal and pharmaceutical industries. Despite their various biological activities, the potential of EGEOs
Hua Zhu, Xin Zhong
doaj   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Inulavosin, a Melanogenesis Inhibitor, Leads to Mistargeting of Tyrosinase to Lysosomes and Accelerates its Degradation [PDF]

, 2008
The melanosome is a highly specialized organelle where melanin is synthesized. Tyrosinase and tyrosinase-related protein-1 (Tyrp1) are major melanosomal membrane proteins and key enzymes for melanin synthesis in melanocytes.
Sadaki Yokota, Akitsugu Yamamoto, Tanaka, Yoshitaka, Katagiri, Takayuki, Yamamoto, Akitsugu, Yokota, Sadaki, Yoshitaka Tanaka, Motokawa, Tomonori, Takayuki Katagiri, Himeno, Masaru, Tomonori Motokawa, Hideaki Fujita, Fujita, Hideaki, Masaru Himeno   +13 more
core   +1 more source

Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Flavonoids are widely distributed in plants and constitute the most common polyphenolic phytoconstituents in the human diet. In this study, the in vitro inhibitory activity of 44 different flavonoids (1–44) against mushroom tyrosinase was studied, and an
Katarzyna Jakimiuk, Suat Sari, Robert Milewski, Claudiu T. Supuran, Didem Şöhretoğlu, Michał Tomczyk   +5 more
doaj   +1 more source

Integrated phytochemical and bioactivity profiling of Xanthium strumarium fruits from Korea and China: Implications for origin‐specific quality specification

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Geographic origin influences the phytochemical composition and biological activities of medicinal plant resources. Xanthium strumarium L. (XS) fruit is widely used in East Asian traditional medicine. However, current pharmacopeial standards primarily recognize Chinese‐derived material, despite the availability and traditional use of
Eunsu Song, Seung‐Min Oh, Jiyeon Chun, Jinah Hwang   +3 more
wiley   +1 more source

Design, synthesis and biological evaluation of novel kojic acid triazole hybrids as tyrosinase inhibitors and antibrowning agents

Scientific Reports
In this study, two series of kojic acid triazole hybrids, namely 6a–6p and 13a–13t, were designed and synthesized. Subsequently, their biological activities including anti-tyrosinase, antioxidant, and as anti-browning effects were investigated.
Dan Liu, Junyuan Tang, Sheng Tao, Dahan Wang, Jinbing Liu   +4 more
doaj   +1 more source

Vitiligo and Skin Cancer Risk: A Systematic Review and Meta‐Analysis With Subtype and Phototherapy Stratification

JEADV Clinical Practice, EarlyView.
Vitiligo was associated with directionally lower odds of melanoma and non‐melanoma skin cancer in this systematic review and meta‐analysis of 14 studies. A statistically significant inverse association was observed for squamous cell carcinoma. Phototherapy exposure showed higher, but non‐significant, point estimates for melanoma and non‐melanoma skin ...
Simonetta I. Gaumond, Luis F. Andrade, Peyton V. Warp, Isabella Kamholtz, Sophie Shrestha, Hannah Metheny, Alireza Abdshah, Paolo Romanelli, Joaquin J. Jimenez   +8 more
wiley   +1 more source

POTENCY OF BELIMBING WULUH (AVERRHOA BILIMBI) AS ANTIOXIDANT AND TYROSINASE INHIBITOR FOR SKIN WHITENING PRODUCTS

, 2019
Hyperpigmentation is an event that occurs due to excessive production of skin pigments, where the presence of melanin. Belimbing wuluh as Indonesian plant is rich compounds that function as antioxidants and tyrosinase inhibitor.
Ririn Suharsanti 1 *, Nining Sugihartini 2, Endang Lukitaningsih 3, Muhammad Ryan Radix Rahardhian 1
core   +1 more source