Results 111 to 120 of about 12,040 (235)

Collagen Hydrolysates From Tilapia Skin: Discovery of LGPL as a Bioactive Peptide Targeting RPN2 to Attenuate UVB‐Induced Photoaging

Food Frontiers, Volume 7, Issue 4, July 2026.
The key findings and main message of the work: (1) A novel collagen tetrapeptide LGPL with potent anti‐photoaging activity was identified. (2) LGPL mitigates skin photoaging by promoting cellular repair, reducing oxidative stress, and enhancing Type I collagen synthesis. (3) RPN2 is confirmed as the direct intracellular target of LGPL.
Xuejia Hu, Yanfei Jiang, Yongkang Luo, Chunyue Zhao   +3 more
wiley   +1 more source

Molecular docking Study of Nuciferine as a Tyrosinase Inhibitor and Its Therapeutic Potential for Hyperpigmentation. [PDF]

Genomics Inform, 2023
Veerichetty V, Saravanabavan I.
europepmc   +1 more source

From Metabolites to Mechanisms: Scorzonera parviflora Aerial Parts and Roots Extracts Profiled by UPLC‐ESI‐MS/MS, In Vitro/In Silico Tests, and Network Analysis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Scorzonera parviflora is considered a promising candidate for applications in the pharmaceutical, nutraceutical, and natural product industries. ABSTRACT In the present study, the extraction of Scorzonera parviflora aerial parts and roots was performed using four solvents, namely ethyl acetate (EA), ethanol, ethanol/water, and water. The total phenolic
Gokhan Zengin, Nilofar Nilofar, Gunes Ak, Eliana Fernandes, Luísa Custódio, Maria João Rodrigues, Shaza Aly, Omayma A. Eldahshan, Abdel Nasser Singab, Evren Yildiztugay, Milena Terzic, Meng‐Yao Li   +11 more
wiley   +1 more source

Synthesis, biological evaluation, molecular docking, MD simulation and DFT analysis of new 3-hydroxypyridine-4-one derivatives as anti-tyrosinase and antioxidant agents

Heliyon
In the present study, ten new substituted 3-hydroxypyridine-4-one derivatives were synthesized in a four-step method, and their chemical structures were confirmed using various spectroscopic techniques.
Sara Sadeghian, Fateme Zare, Mehdi Khoshneviszadeh, Arian Fathi Hafshejani, Farhang Salahshour, Ahmadreza Khodabakhshloo, Lotfollah Saghaie, Ghazal Goshtasbi, Zahra Sarikhani, Alireza Poustforoosh, Razieh Sabet, Hossein Sadeghpour   +11 more
doaj   +1 more source

Evaluation of Enzyme Inhibition and Kinetic Profiles of Origanum Essential Oils on Metabolic and Central Nervous System Targets

Natural Sciences, Volume 6, Issue 3, July 2026.
The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato, Lucia Caputo, Laura De Martino, Daniela Grulova, Barbara Borczak, Joanna Kapusta‐Duch, Vincenzo De Feo   +6 more
wiley   +1 more source

EVALUATION OF BILE ACIDS-BINDING CAPACITY AND TYROSINASE INHIBITOR POTENCY OF NOVEL PEPTIDES PREPARED FROM AGRICULTURAL WASTES VIA ENZYMATIC HYDROLYSIS

, 2020
The objective of this study was to prepare bile acidsbinding and tyrosinase inhibitory peptides for industrial potential application. Proteins were extracted from Brassica olercea (cauliflower) midribs, Corchorus olitorius (corchorus) stems and Vicia ...
Sanaa T. El-Sayed, Rehab A. Al- Azzouny, Ola S. Ali   +2 more
core  

Purification and Determination of the Chemical Structure of the Tyrosinase Inhibitor Produced by Trichoderma viride Strain H1-7 from a Marine Environment

, 2008
Tyrosinase is a key enzyme in the synthesis of melanin and is widely distributed in animals, plants, and microorganisms. As excessive melanin production causes not only hyperpigmenting effects on human skin but also melanosis in various foods, an ...
Miyamoto, Katsuhiro, 濱田, 奈保子, Imada, Chiaki, Kobayashi, Takeshi, コバヤシ, タケシ, Hamada, Naoko, イマダ, チアキ, 小林, 武志, Yamada, Katsuhisa, ハマダ, ナオコ, 今田, 千秋, Tsuchiya, Takahiro, Satoh, Naoko, 佐藤, 奈保子, Minoura, Katsuhiko, Usami, Yoshihide, Tsujibo, Hiroshi, サトウ, ナオコ   +17 more
core   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, Volume 40, Issue 7, Page 4588-4610, July 2026.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Hop Tannins as Multifunctional Tyrosinase Inhibitor: Structure Characterization, Inhibition Activity, and Mechanism. [PDF]

Antioxidants (Basel), 2022
Liu J, Chen Y, Zhang X, Zheng J, Hu W, Teng B.   +5 more
europepmc   +1 more source

Kojic acid-derived tyrosinase inhibitors: synthesis and bioactivity

Pharmaceutical and Biomedical Research, 2015
Tyrosinase is a key enzyme for melanin biosynthesis, catalyzing the oxidation of L-tyrosine to L-dopaquinone. The tyrosinase inhibition is an effective approach to control hyperpigmentation in human skin and enzymatic browning in fruits and vegetables ...
Seyedeh Mahdieh Hashemi, Saeed Emami
doaj