Results 31 to 40 of about 207,078 (211)

A pilot study on nitration/dysfunction of NK1 segment of myogenic stem cell activator HGF

open access: yesBiochemistry and Biophysics Reports, 2022
Protein tyrosine residue (Y) nitration, a post-translational chemical-modification mode, has been associated with changes in protein activity and function; hence the accumulation of specific nitrated proteins in tissues may be used to monitor the onset ...
Alaa Elgaabari   +12 more
doaj   +1 more source

Protein nitration: A connecting bridge between nitric oxide (NO) and plant stress

open access: yesPlant Stress, 2021
Nitric oxide (•NO) is a free radical which exerts a myriad of functions in the physiology of higher plants either under physiological and environmental stress conditions.
Francisco J. Corpas   +2 more
doaj   +1 more source

Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols

open access: yesAngewandte Chemie, EarlyView.
Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione   +7 more
wiley   +2 more sources

Probing Tyrosine Nitration with a Small TbIII-Metallopeptide [PDF]

open access: yes, 2023
Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG[Abstract] Tyrosine nitration, a post-translational modification (PTM) that takes place under nitrosative stress conditions, occurs through a non-enzymatic peroxynitrite-mediated ...
Sánchez-Fernández, Rosalía   +3 more
core   +1 more source

RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury

open access: yesRedox Biology, 2021
Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy.
Ting Wang   +10 more
doaj   +1 more source

Target of Tyrosine Nitration in Diabetic Rat Retina [PDF]

open access: yesMolecular & Cellular Proteomics, 2008
Diabetic retinopathy, a retinal vascular disease, is inhibited in animals treated with aminoguanidine, an inhibitor of inducible nitric-oxide synthase. This treatment also reduces retinal protein nitration, which is greater in diabetic rat retina than nondiabetic retina.
Xianquan, Zhan   +5 more
openaire   +2 more sources

A possible link between astrocyte activation and tau nitration in Alzheimer's disease

open access: yesNeurobiology of Disease, 2008
Alzheimer's disease (AD) pathology has been characterized, in part, by the self-assembly of the tau molecule into neurofibrillary tangles (NFT). While different post-translational modifications have been identified that accelerate tau aggregation ...
Juan F. Reyes   +6 more
doaj   +1 more source

Tyrosine residues predicted to undergo tyrosine nitration.

open access: yes, 2018
Tyrosine residues predicted to undergo tyrosine nitration.
Prachi Jain (3362243)   +1 more
core   +1 more source

Identification and Relative Quantification of Tyrosine Nitration in a Model Peptide Using Two-Dimensional Infrared Spectroscopy [PDF]

open access: yes, 2014
Nitration of tyrosine in proteins and peptides is a post-translational modification that occurs under conditions of oxidative stress. It is implicated in a variety of medical conditions, including neurodegenerative and cardiovascular diseases.
Rezende Valim, Lays   +34 more
core   +1 more source

iNitroY-Deep: Computational Identification of Nitrotyrosine Sites to Supplement Carcinogenesis Studies Using Deep Learning

open access: yesIEEE Access, 2021
In biological systems, Nitration is a crucial post-translational modification which occurs on various amino acids. Nitration of Tyrosine is regarded as nitorsative stress biomarker resulting in the formation of peroxynitrite and other reactive and ...
Sheraz Naseer   +3 more
doaj   +1 more source

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