Results 31 to 40 of about 207,078 (211)
A pilot study on nitration/dysfunction of NK1 segment of myogenic stem cell activator HGF
Protein tyrosine residue (Y) nitration, a post-translational chemical-modification mode, has been associated with changes in protein activity and function; hence the accumulation of specific nitrated proteins in tissues may be used to monitor the onset ...
Alaa Elgaabari +12 more
doaj +1 more source
Protein nitration: A connecting bridge between nitric oxide (NO) and plant stress
Nitric oxide (•NO) is a free radical which exerts a myriad of functions in the physiology of higher plants either under physiological and environmental stress conditions.
Francisco J. Corpas +2 more
doaj +1 more source
Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols
Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione +7 more
wiley +2 more sources
Probing Tyrosine Nitration with a Small TbIII-Metallopeptide [PDF]
Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG[Abstract] Tyrosine nitration, a post-translational modification (PTM) that takes place under nitrosative stress conditions, occurs through a non-enzymatic peroxynitrite-mediated ...
Sánchez-Fernández, Rosalía +3 more
core +1 more source
Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy.
Ting Wang +10 more
doaj +1 more source
Target of Tyrosine Nitration in Diabetic Rat Retina [PDF]
Diabetic retinopathy, a retinal vascular disease, is inhibited in animals treated with aminoguanidine, an inhibitor of inducible nitric-oxide synthase. This treatment also reduces retinal protein nitration, which is greater in diabetic rat retina than nondiabetic retina.
Xianquan, Zhan +5 more
openaire +2 more sources
A possible link between astrocyte activation and tau nitration in Alzheimer's disease
Alzheimer's disease (AD) pathology has been characterized, in part, by the self-assembly of the tau molecule into neurofibrillary tangles (NFT). While different post-translational modifications have been identified that accelerate tau aggregation ...
Juan F. Reyes +6 more
doaj +1 more source
Tyrosine residues predicted to undergo tyrosine nitration.
Tyrosine residues predicted to undergo tyrosine nitration.
Prachi Jain (3362243) +1 more
core +1 more source
Identification and Relative Quantification of Tyrosine Nitration in a Model Peptide Using Two-Dimensional Infrared Spectroscopy [PDF]
Nitration of tyrosine in proteins and peptides is a post-translational modification that occurs under conditions of oxidative stress. It is implicated in a variety of medical conditions, including neurodegenerative and cardiovascular diseases.
Rezende Valim, Lays +34 more
core +1 more source
In biological systems, Nitration is a crucial post-translational modification which occurs on various amino acids. Nitration of Tyrosine is regarded as nitorsative stress biomarker resulting in the formation of peroxynitrite and other reactive and ...
Sheraz Naseer +3 more
doaj +1 more source

