Results 181 to 190 of about 25,325 (230)
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Ubiquinol-3 and Ubiquinol-7 Exhibit Similar Antioxidant Activity in Model Membranes
Free Radical Research Communications, 1993This study was undertaken to compare, on a kinetic basis, the antioxidant efficiency of an ubiquinol homologue having a short isoprenoid side-chain length, such as ubiquinol-3, with that of the long chain ubiquinol-7, by determining their rate constants of inhibition with respect to alpha-tocopherol.
D, Fiorentini, L, Cabrini, L, Landi
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Antioxidant-derived prooxidant formation from ubiquinol
Free Radical Biology and Medicine, 1998Ubiquinol (QH2) is increasingly used as antioxidant for the treatment of a variety of diseases and the modulation of biological aging; however, the biological significance of secondary reaction products has been disregarded so far. Our studies on the antioxidant activity of ubiquinol in peroxidizing lipid membranes demonstrate the existence of ...
H, Nohl, L, Gille, A V, Kozlov
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Stability studies of ubiquinol in plasma
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2003Background: Ubiquinol is a sensitive redox marker in the first line of the antioxidative defence mechanism and is increasingly being measured in oxidation studies. Because of its apparent instability during storage and processing, we compared various storage conditions.
Hectors, M.P.C. +3 more
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Ubiquinol: an endogenous antioxidant in aerobic organisms
The Clinical Investigator, 1993Ubiquinone (coenzyme Q), in addition to its function as an electron and proton carrier in mitochondrial and bacterial electron transport linked to ATP synthesis, acts in its reduced form (ubiquinol) as an antioxidant, preventing the initiation and/or propagation of lipid peroxidation in biological membranes and in serum low-density lipoprotein.
L, Ernster, P, Forsmark-Andrée
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Crystallization of mitochondrial ubiquinol-cytochrome c reductase
Biochemistry, 1991Ubiquinol-cytochrome c reductase of beef heart mitochondria was crystallized in the presence of decanoyl-N-methylglucamide, heptanetriol, and sodium chloride with poly(ethylene glycol) as precipitant. The largest crystal has dimensions of 4 x 2 x 1 mm. The crystalline enzyme is composed of 10 subunits.
W H, Yue, Y P, Zou, L, Yu, C A, Yu
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Zeitschrift für Orthomolekulare Medizin, 2016
Der Mikronahrstoff Ubiquinol ist ein essenzieller Bestandteil der mitochondrialen Atmungskette und damit verantwortlich fur die Energiegewinnung in den Zellen. Zudem schutzt er als Antioxidans vor freien Radikalen, die bei sportlicher Aktivitat vermehrt gebildet werden, und wirkt entzundungshemmend.
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Der Mikronahrstoff Ubiquinol ist ein essenzieller Bestandteil der mitochondrialen Atmungskette und damit verantwortlich fur die Energiegewinnung in den Zellen. Zudem schutzt er als Antioxidans vor freien Radikalen, die bei sportlicher Aktivitat vermehrt gebildet werden, und wirkt entzundungshemmend.
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Mechanisms and dynamics of antioxidant action of ubiquinol
Molecular Aspects of Medicine, 1997The mechanisms and dynamics of antioxidant action of ubiquinol have been studied. Ubiquinol scavenges peroxyl radical faster than alpha-tocopherol. However, it is autooxidized rapidly to give hydroperoxyl radical and/or superoxide and hence its antioxidant potency is smaller than that of alpha-tocopherol.
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Myocardial energetics and ubiquinol in diastolic heart failure
Nursing & Health Sciences, 2014AbstractDiastolic heart failure, or heart failure with preserved ejection fraction, is a leading cause of morbidity and mortality. There are no current therapies effective in improving outcomes for these patients. The aim of this article is to review the literature and examine the role of coenzyme Q10 in heart failure with preserved ejection fraction ...
Angelina, Bates +4 more
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Reactivity of ubiquinones and ubiquinols with free radicals
Free Radical Research, 2001The reactivity of quinones 1-4 and of the corresponding quinols 5-8 towards carbon- and oxygen-centred radicals were studied. All quinones bearing at least one nuclear position free, readily react with alkyl and phenyl radicals to afford the alkylated quinones 12-24; however, quinones 1 and 3 reacted with 2-cyano-2-propyl radical to yield products (the
E, Giorgini +5 more
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Dynamics of antioxidant action of ubiquinol: A reappraisal
BioFactors, 1999AbstractThe dynamics of action of ubiquinol as an antioxidant against lipid peroxidation was reinvestigated and compared with that ofα‐tocopherol. It was found that ubiquinol was 2.5 and 1.9 times more reactive thanα‐tocopherol toward phenoxyl and peroxyl radicals, respectively, at 25°C in ethanol and that it was capable of donating two hydrogen atoms ...
H, Shi, N, Noguchi, E, Niki
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