Results 1 to 10 of about 63,167 (252)

The NADH-ubiquinone reductase and succinate dehydrogenase activity in the rat kidney mitochondria under the conditions of different protein and sucrose content in the diet [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2022
The NADH-ubiquinone reductase (EC 7.1.1.2) and succinate dehydrogenase (EC 1.3.5.1) activity, the levels of total ubiquinone and its redox forms, and the degree of oxidative modification of mitochondrial proteins in the rat kidney were investigated.
O. M. Voloshchuk   +2 more
doaj   +1 more source

Stability of Reduced and Oxidized Coenzyme Q10 in Finished Products

open access: yesAntioxidants, 2021
The efficiency of coenzyme Q10 (CoQ10) supplements is closely associated with its content and stability in finished products. This study aimed to provide evidence-based information on the quality and stability of CoQ10 in dietary supplements and ...
Žane Temova Rakuša   +2 more
doaj   +1 more source

Ubiquinone Supplementation with 300 mg on Glycemic Control and Antioxidant Status in Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial

open access: yesAntioxidants, 2020
The aim of this study is to investigate the glycemic profile, oxidative stress, and antioxidant capacity in athletes after 12 weeks of ubiquinone supplementation. It was a double-blinded, randomized, parallel, placebo-controlled study.
Chien-Chang Ho   +6 more
doaj   +1 more source

Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death. [PDF]

open access: yesPLoS ONE, 2010
Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied ...
Flavien Devun   +5 more
doaj   +1 more source

An Investigation into the Effects of Ubiquinone on Inflammation, Diabetic Myopathy and Endotheliopathy, and CBC Parameters in Diabetic Rats

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2023
Oxidative stress and inflammation are connected to the development of metabolic disorders, such as diabetes. Diabetic-related oxidative stress is caused by the overproduction of oxidative-free radicals, which have been implicated in the mechanism of ...
Yousif Jameel Jbrael   +1 more
doaj   +1 more source

A water soluble CoQ10 formulation improves intracellular distribution and promotes mitochondrial respiration in cultured cells. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Mitochondria are both the cellular powerhouse and the major source of reactive oxygen species. Coenzyme Q(10) plays a key role in mitochondrial energy production and is recognized as a powerful antioxidant.
Christian Bergamini   +4 more
doaj   +1 more source

RegB Kinase Activity Is Controlled in Part by Monitoring the Ratio of Oxidized to Reduced Ubiquinones in the Ubiquinone Pool

open access: yesmBio, 2010
RegB is a membrane-spanning sensor kinase responsible for redox regulation of a wide variety of metabolic processes in numerous proteobacterial species. Here we show that full-length RegB purified from Escherichia coli membranes contains bound ubiquinone.
Jiang Wu, Carl E. Bauer
doaj   +1 more source

Ubiquinone [Q10] and Dentate Gyrus Ischaemia Reperfusion Injury in a Rat Model of Brain Ischaemia

open access: yesArchives of Advances in Biosciences, 2023
Introduction: This research was conducted to evaluate the effect of ubiquinone following ischemia/reperfusion on dentate gyrus in Wistar rats. Materials and Methods: Twenty-four Rats were randomly assigned to four groups [n=6].
Niloofar Talebi Tadi   +3 more
doaj   +1 more source

Plasma coenzyme Q10 levels in type 2 diabetic patients with retinopathy [PDF]

open access: yesInternational Journal of Ophthalmology, 2013
AIM: To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.METHODS: Patients with type 2 diabetes and PDRP were determined to be the case group (n=50).
Orhan Ates   +9 more
doaj   +1 more source

Coenzyme Q10 Reduces Infarct Size in Animal Models of Myocardial Ischemia-Reperfusion Injury: A Meta-Analysis and Summary of Underlying Mechanisms

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectiveEffective interventions that might limit myocardial ischemia-reperfusion (I/R) injury are still lacking. Coenzyme Q10 (CoQ10) may exert cardioprotective actions that reduce myocardial I/R injury.
Kamal Awad   +5 more
doaj   +1 more source

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