Results 1 to 10 of about 67,397 (350)
RegB Kinase Activity Is Controlled in Part by Monitoring the Ratio of Oxidized to Reduced Ubiquinones in the Ubiquinone Pool [PDF]
mBio, 2010 RegB is a membrane-spanning sensor kinase responsible for redox regulation of a wide variety of metabolic processes in numerous proteobacterial species. Here we show that full-length RegB purified from Escherichia coli membranes contains bound ubiquinone.
Jiang Wu, Carl E. Bauer
doaj +3 more sources
Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death. [PDF]
PLoS ONE, 2010 Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied ...
Flavien Devun +5 more
doaj +6 more sources
The ubiquinone content of animal tissues. A survey of the occurrence of ubiquinone in vertebrates [PDF]
Biochemical Journal, 1967 1. A method was developed for the analysis of ubiquinone in animal tissues and the recovery of added ubiquinone tested in liver of the rat, Crocodylus porosus and Squalus acanthias. 2. The ubiquinone content of heart, liver and gut (or breast muscle in birds) was measured in 67 different animal species, selected to be representative of all the ...
A. T. Diplock, GAD Haslewood
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Ubiquinone and Tocopherol in Birds [PDF]
Nature, 1961 UNLIKE the rat and the rabbit, it seems from nutritional studies made by several groups of workers that the chicken needs little vitamin E, providing its diet contains an adequate supply of selenium and only limited amounts of unsaturated fat1–3. Since tissue-levels of ubiquinone in the rat4 and rabbit5 are high compared with those given for some other
J. Bunyan +3 more
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Current global vitamin and cofactor prescribing practices for primary mitochondrial diseases: Results of a European reference network survey. [PDF]
J Inherit Metab DisAbstract Primary mitochondrial diseases (PMD) account for a group of approximately 400 different genetic disorders with diverse clinical presentations and pathomechanisms. Although each individual disorder is rare, collectively they represent one of the largest groups in the field of inherited metabolic disorders.
Neugebauer J +8 more
europepmc +2 more sources
Preparation and Evaluation of Complexed Ubiquinone (Coenzyme Q10) Antiaging Hyaluronic Acid-Vitamin C Serum for Skin Care. [PDF]
J Cosmet DermatolABSTRACT Background Coenzyme Q10 (CoQ10) is widely recognized for its powerful antioxidant properties, sparking considerable interest in its application within skincare treatments. However, its inherently poor water solubility has posed a major challenge in formulating effective skincare products.
Arkan Yousif H +5 more
europepmc +2 more sources
Journal of Biological Chemistry, 1974 Abstract The total biosynthesis of ubiquinone-9 from p-hydroxy[U-14C]benzoate has been demonstrated in mitochondria isolated from rat liver slices preincubated with mevalonic acid. Two partial reactions were also demonstrated. These were the conversion of p-hydroxybenzoate to 5-demethoxyubiquinone-9 and sequentially, the conversion of 5 ...
Bernard L. Trumpower +2 more
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The NADH-ubiquinone reductase and succinate dehydrogenase activity in the rat kidney mitochondria under the conditions of different protein and sucrose content in the diet [PDF]
The Ukrainian Biochemical Journal, 2022 The NADH-ubiquinone reductase (EC 7.1.1.2) and succinate dehydrogenase (EC 1.3.5.1) activity, the levels of total ubiquinone and its redox forms, and the degree of oxidative modification of mitochondrial proteins in the rat kidney were investigated.
O. M. Voloshchuk +2 more
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Advanced Science, Volume 9, Issue 35, December 19, 2022., 2022 Kyat2‐mediated metabolic rewiring of the kynurenine pathway partitions it away from de novo nicotinamide adenine dinucleotide (NAD) biosynthesis in hepatic ischemia–reperfusion injury. Single intraperitoneal dose of nicotinamide mononucleotide post‐reperfusion effectively boosts NAD and reduces liver damage, providing proof of concept that replenishing
Bowen Xu +11 more
wiley +1 more source
Stability of Reduced and Oxidized Coenzyme Q10 in Finished Products
Antioxidants, 2021 The efficiency of coenzyme Q10 (CoQ10) supplements is closely associated with its content and stability in finished products. This study aimed to provide evidence-based information on the quality and stability of CoQ10 in dietary supplements and ...
Žane Temova Rakuša +2 more
doaj +1 more source