Results 21 to 30 of about 17,362,245 (308)

Human Viral Oncoproteins and Ubiquitin–Proteasome System [PDF]

Global Medical Genetics
Some human cancers worldwide may be related to human tumor viruses. Knowing, controlling, and managing the viruses that cause cancers remain a problem.
Zahra Rafiei Atani, Sareh Sadat Hosseini, Hossein Goudarzi, Ebrahim Faghihloo   +3 more
doaj   +2 more sources

Bombyx mori C-Type Lectin 16 Inhibits BmNPV Proliferation by Degrading Viral Protein Bm9 via Ubiquitin–Proteasome System [PDF]

Biomolecules
Sun X, Cui C, Huang G, Zou X, Yu S, Du X, Xu X, Chen J, He X, Wang Y, Zhu L.   +10 more
europepmc   +2 more sources

Regulatory mechanisms for Snail protein stability: ubiquitin-proteasome system and chaperone-mediated autophagy. [PDF]

Exp Mol Med
Kim M, Hong KS, Kim T, Ryu KJ, Yoo J.
europepmc   +3 more sources

A Conserved Magnaporthe oryzae Effector Counteracts the Rice Ubiquitin-Proteasome System by Disrupting the E2 Function to Suppress Immunity. [PDF]

Plant Biotechnol J
Wang M, Wang R, Xiong Y, You X, Zhang F, Mao X, He F, Tao H, Jiang S, Fang L, Xu X, Wang J, Hao Z, Hou Y, Zhang H, Wang J, Zheng W, Sun W, Wang GL, Ning Y.   +19 more
europepmc   +2 more sources

Editorial: The ubiquitin-proteasome system and cellular signaling: mechanisms and regulatory roles in cancer and infectious diseases. [PDF]

Front Cell Dev Biol
Islam S, Hussain A, Alam A, Ansari MO, Saeed H, Khan S.   +5 more
europepmc   +3 more sources

Chlorogenic acid modulates the ubiquitin–proteasome system in stroke animal model

Laboratory Animal Research, 2022
Background Chlorogenic acid, a phenolic compound, has potent antioxidant and neuroprotective properties. The ubiquitin–proteasome system is an important regulators of neurodevelopment and modulators of neuronal function.
Murad-Ali Shah, Ju-Bin Kang, Phil-Ok Koh
doaj   +1 more source

Balanced activities of Hsp70 and the ubiquitin proteasome system underlie cellular protein homeostasis

Frontiers in Molecular Biosciences, 2023
To counteract proteotoxic stress and cellular aging, protein quality control (PQC) systems rely on the refolding, degradation and sequestration of misfolded proteins.
Areeb Jawed, Areeb Jawed, Chi-Ting Ho, Chi-Ting Ho, Tomas Grousl, Tomas Grousl, Aseem Shrivastava, Aseem Shrivastava, Thomas Ruppert, Bernd Bukau, Bernd Bukau, Axel Mogk, Axel Mogk   +12 more
doaj   +1 more source

Substrate-specific effects of natural genetic variation on proteasome activity.

PLoS Genetics, 2023
Protein degradation is an essential biological process that regulates protein abundance and removes misfolded and damaged proteins from cells. In eukaryotes, most protein degradation occurs through the stepwise actions of two functionally distinct ...
Mahlon A Collins, Randi Avery, Frank W Albert   +2 more
doaj   +1 more source

Targeted Protein Degradation: Principles and Applications of the Proteasome

Cells, 2023
The proteasome is a multi-catalytic protease complex that is involved in protein quality control via three proteolytic activities (i.e., caspase-, trypsin-, and chymotrypsin-like activities).
Yosup Kim, Eun-Kyung Kim, Yoona Chey, Min-Jeong Song, Ho Hee Jang   +4 more
doaj   +1 more source

Retinoic acid regulates the ubiquitin–proteasome system in a middle cerebral artery occlusion animal model

Laboratory Animal Research, 2022
Background Retinoic acid is a major metabolite of vitamin A and exerts beneficial effects including anti-oxidant and anti-inflammatory activities in neurons.
Ju-Bin Kang, Murad-Ali Shah, Dong-Ju Park, Phil-Ok Koh   +3 more
doaj   +1 more source