Results 11 to 20 of about 18,434,088 (294)

Poxvirus Exploitation of the Ubiquitin-Proteasome System [PDF]

Viruses, 2010
Ubiquitination plays a critical role in many cellular processes. A growing number of viruses have evolved strategies to exploit the ubiquitin-proteasome system, including members of the Poxviridae family. Members of the poxvirus family have recently been
Alastair Teale, Qian Wang, Kristin Burles, Michele Barry, Kelly Mottet, Nicholas van Buuren   +5 more
doaj   +4 more sources

Intracellular Dynamics of the Ubiquitin-Proteasome-System [v1; ref status: indexed, http://f1000r.es/5o5] [PDF]

F1000Research, 2015
The ubiquitin-proteasome system is the major degradation pathway for short-lived proteins in eukaryotic cells. Targets of the ubiquitin-proteasome-system are proteins regulating a broad range of cellular processes including cell cycle progression, gene ...
Maisha Chowdhury, Cordula Enenkel
doaj   +5 more sources

The ubiquitin-proteasome system

Journal of Biosciences, 2006
The 2004 Nobel Prize in chemistry for the discovery of protein ubiquitination has led to the recognition of cellular proteolysis as a central area of research in biology.
Kumar, Anujith, Chandu, Dilip, Tahiliani, Pankaj, Nandi, Dipankar   +3 more
core   +5 more sources

Intracellular Dynamics of the Ubiquitin-Proteasome-System [version 2; referees: 3 approved]

F1000Research, 2015
The ubiquitin-proteasome system is the major degradation pathway for short-lived proteins in eukaryotic cells. Targets of the ubiquitin-proteasome-system are proteins regulating a broad range of cellular processes including cell cycle progression, gene ...
Maisha Chowdhury, Cordula Enenkel
doaj   +2 more sources

Targeting the Ubiquitin–Proteasome System for Cancer [PDF]

MedComm
Ubiquitin is a highly conserved small molecule that exists in large quantities in eukaryotic cells and plays a crucial role in protein quality control by phagocytosis and degradation of ubiquitin‐modified proteins.
Zhaoyun Liu, Jiao Lai, Ziyu Ma, Jianhua Pan, Chun Yang, Rong Fu   +5 more
doaj   +2 more sources

ROLE OF UBIQUITIN PROTEASOME SYSTEM IN GASTRIC CANCER PATHOGENESIS

Сибирский онкологический журнал, 2016
The review presents data on the ubiquitin-proteasome system participation in pathogenesis of gastric cancer. The role of proteasome system in regulation of cell cycle, angiogenesis and tumor metastasis has been shown.
E. V. Ivanova, I. V. Kondakova, О. V. Cheremisina, S. G. Afanasyev   +3 more
doaj   +1 more source

Transcriptional control and the ubiquitin-proteasome system

, 2008
Regulation of transcription is a critically important process that controls development, differentiation, and the maintenance of cellular homeostasis.
Geng, F., Daulny, A., Collins, G. A., Guzzardo, P. M., P. Guzzardo, Tansey, W. P., Leung, A., A. Leung, A. Daulny, G. Collins, F. Geng, W. P. Tansey   +11 more
core   +3 more sources

Ubiquitin proteasome system in cardiac fibrosis [PDF]

Journal of Advanced Research
Background: Cardiac fibrosis, including reactive fibrosis and replacement fibrosis, is a common pathological process in most cardiovascular diseases.
Linqi Zeng, Xiaokai Zhang, Zihang Huang, Shuai Song, Mohan Li, Tongyao Wang, Aijun Sun, Junbo Ge   +7 more
doaj   +2 more sources

The Ubiquitin-Proteasome System: A Key Regulatory Hub in Myocarditis Leading to Dilated Cardiomyopathy [PDF]

J Inflamm Res
Xiang Yin, Dongfei Wang, Jialan Lyu, Jie Ding, Zhicheng Pan, Kai Wang, Xiaogang Guo Department of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Xiaogang Guo ...
Yin X, Pan Z, Lyu J, Guo X, Wang D, Ding J, Wang K   +6 more
core   +2 more sources

The Ubiquitin-Proteasome System in Neurodegeneration [PDF]

Antioxidants & Redox Signaling, 2014
Significance: Impairment of the ubiquitin-proteasome system (UPS) has been implicated in the pathogenesis of a wide variety of neurodegenerative disorders, including Alzheimer's, Parkinson's, and Huntington's diseases.
Chris McKinnon, Sarah J. Tabrizi
openaire   +3 more sources