Results 181 to 190 of about 187,561 (340)
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination [PDF]
, 2000 Olivier Staub +8 more
openalex +1 more source
A Novel OsMPK6‐OsMADS47‐PPKL1/3 Module Controls Grain Shape and Yield in Rice
Advanced Science, EarlyView.OsMADS47 is identified as a key regulator governing rice grain morphology. Phosphorylation‐dependent regulation of its activity directs the development of slender versus round grains, modulating both yield and appearance. This mechanism bridges cellular signaling with transcriptional regulation, establishing a molecular framework for grain optimization.
Jingjing Fang +9 more
wiley +1 more source
Harnessing the Ubiquitination Machinery to Target the Degradation of Specific Cellular Proteins [PDF]
, 2000 Pengbo Zhou +3 more
openalex +1 more source
Advanced Science, EarlyView.Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo +20 more
wiley +1 more source
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
Advanced Science, EarlyView.These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu +17 more
wiley +1 more source
Akr1p and the Type I Casein Kinases Act prior to the Ubiquitination Step of Yeast Endocytosis: Akr1p Is Required for Kinase Localization to the Plasma Membrane [PDF]
, 2000 Ying Feng, Nicholas G. Davis
openalex +1 more source
Advanced Science, EarlyView.ID1 is regulated by E3 ligase TRIM21, which adds non‐degradative K11‐linked ubiquitin at Lys91, disrupting ID1‐TCF12 binding and freeing TCF12 to upregulate copper transporter SLC31A1. Enhanced SLC31A1 elevates intracellular copper, triggers cuproptosis, and inhibits ESCC growth.
Lei Li +6 more
wiley +1 more source
Nedd8 Modification of Cul-1 Activates SCFβTrCP-Dependent Ubiquitination of IκBα
, 2000 Margaret Read +10 more
openalex +1 more source
The hPLIC Proteins May Provide a Link between the Ubiquitination Machinery and the Proteasome [PDF]
, 2000 Maurits F. Kleijnen +7 more
openalex +1 more source
Role of histone H2A ubiquitination in Polycomb silencing
Nature, 2004 Hengbin Wang +6 more
semanticscholar +1 more source