Results 1 to 10 of about 60,978 (228)

Structure-function and engineering of plant UDP-glycosyltransferase [PDF]

Computational and Structural Biotechnology Journal, 2023
Natural products synthesized by plants have substantial industrial and medicinal values and are therefore attracting increasing interest in various related industries.
Mengya Wang, Qiushuang Ji, Bin Lai, Yirong Liu, Kunrong Mei   +4 more
doaj   +5 more sources

Targeting UDP-Glycosyltransferase, Glucosamine-6-Phosphate Synthase and Chitin Synthase by Using Bioactive 1,8 Cineole for “Aspergillosis” Fungal Disease Mutilating COVID-19 Patients: Insights from Molecular Docking, Pharmacokinetics and In-vitro Studies [PDF]

Chemistry Africa, 2022
SARS-CoV-2 (COVID-19)-associated co-infections like “Aspergillosis”, has recently baffled the world. Due to its key role in cell wall synthesis, in the present study UDP-glycosyltransferase, glucosamine-6-phosphate synthase and chitin synthase have been ...
Sharma A, Kaur I.
europepmc   +4 more sources

Characterization of UDP-glycosyltransferase family members reveals how major flavonoid glycoside accumulates in the roots of Scutellaria baicalensis [PDF]

BMC Genomics, 2022
Background Flavonoid glycosides extracted from roots of Scutellaria baicalensis exhibit strong pharmaceutical antitumor, antioxidative, anti-inflammatory, and antiviral activities.
Tianlin Pei, Mengxiao Yan, Tian Li, Xiaoqiang Li, Yijia Yin, Mengying Cui, Yumin Fang, Jie Liu, Yu Kong, Ping Xu, Qing Zhao   +10 more
doaj   +4 more sources

UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences [PDF]

International Journal for Parasitology: Drugs and Drug Resistance, 2018
UDP-glycosyltransferases (UGT), catalysing conjugation of UDP-activated sugar donors to small lipophilic chemicals, are widespread in living organisms from bacteria to fungi, plant, or animals.
Petra Matoušková, Lenka Lecová, Roz Laing, Diana Dimunová, Heiko Vogel, Lucie Raisová Stuchlíková, Linh Thuy Nguyen, Pavlína Kellerová, Ivan Vokřál, Jiří Lamka, Barbora Szotáková, Marián Várady, Lenka Skálová   +12 more
doaj   +4 more sources

Efficient Biosynthesis of Gastrodin by UDP-Glycosyltransferase from <i>Rauvolfia serpentina</i>. [PDF]

J Microbiol Biotechnol
Gastrodin, the primary bioactive constituent of Gastrodia elata, possesses numerous remarkable pharmacological properties. In this investigation, UDP-glycosyltransferase from Rauvolfia serpentina (RsUGT) was expressed, subsequently purified and characterized.
Ge L, Xia Y, Xu W, Jia R, Zhang T.
europepmc   +5 more sources

Genome-wide characterization, evolution and expression profiling of UDP-glycosyltransferase family in pomelo (Citrus grandis) fruit [PDF]

BMC Plant Biology, 2020
Background Pomelo is one of the three major species of citrus. The fruit accumulates a variety of abundant secondary metabolites that affect the flavor. UDP-glycosyltransferases (UGTs) are involved in the glycosylation of secondary metabolites.
Boping Wu, Xiaohong Liu, Kai Xu, Bo Zhang   +3 more
doaj   +3 more sources

Genome-wide analysis of UDP-glycosyltransferase gene family and identification of a flavonoid 7-O-UGT (AhUGT75A) enhancing abiotic stress in peanut (Arachis hypogaea L.). [PDF]

BMC Plant Biol, 2023
Background Glycosylation, catalyzed by UDP-glycosyltransferase (UGT), was important for enhancing solubility, bioactivity, and diversity of flavonoids. Peanut ( Arachis hypogaea L.) is an important oilseed and cash crop worldwide.
Ouyang L, Liu Y, Yao R, He D, Yan L, Chen Y, Huai D, Wang Z, Yu B, Kang Y, Jiang H, Lei Y, Liao B, Wang X.   +13 more
europepmc   +2 more sources

Genome-wide analysis of UDP-glycosyltransferase gene family and identification of members involved in flavonoid glucosylation in Chinese bayberry (Morella rubra). [PDF]

Front Plant Sci, 2022
Glycosylation was catalyzed by UDP-glycosyltransferase (UGT) and was important for enriching diversity of flavonoids. Chinese bayberry (Morella rubra) has significant nutritional and medical values because of diverse natural flavonoid glycosides. However,
Ren C, Cao Y, Xing M, Guo Y, Li J, Xue L, Sun C, Xu C, Chen K, Li X.   +9 more
europepmc   +2 more sources

Glutathione Promotes Degradation and Metabolism of Residual Fungicides by Inducing UDP-Glycosyltransferase Genes in Tomato. [PDF]

Front Plant Sci, 2022
Reduced glutathione (GSH) is a key antioxidant, which plays a crucial role in the detoxification of xenobiotics in plants. In the present study, glutathione could reduce chlorothalonil (CHT) residues in tomatoes by inducing the expression of the UDP ...
Yu G, Chen Q, Chen F, Liu H, Lin J, Chen R, Ren C, Wei J, Zhang Y, Yang F, Sheng Y.   +10 more
europepmc   +2 more sources

The Somatic Mutation Landscape of UDP-Glycosyltransferase (UGT) Genes in Human Cancers. [PDF]

Cancers (Basel), 2022
Simple Summary The human UDP-glycosyltransferase (UGT) superfamily is involved in the metabolism of numerous anticancer drugs and endobiotic signaling molecules with pro/anti-cancer activities. Previous studies have shown abundant expression of UGT genes
Hu DG, Marri S, Hulin JA, McKinnon RA, Mackenzie PI, Meech R.   +5 more
europepmc   +2 more sources