Structure-function and engineering of plant UDP-glycosyltransferase [PDF]
Natural products synthesized by plants have substantial industrial and medicinal values and are therefore attracting increasing interest in various related industries.
Mengya Wang +4 more
doaj +4 more sources
UDP-glycosyltransferase confers anthranilic diamide resistance in Bemisia tabaci [PDF]
Introduction: UDP-glycosyltransferases (UGTs) are key Phase II detoxification enzymes in insects, playing a crucial role in resistance to a variety of insecticides, including diamides.
Huiwen Tan +6 more
doaj +4 more sources
A willow UDP-glycosyltransferase involved in salicinoid biosynthesis [PDF]
Abstract The salicinoids are phenolic glycosides that are characteristic secondary metabolites of the Salicaceae, particularly willows and poplars. Despite the well-known pharmacology of salicin, that led to the development of aspirin >100 years ago, the biosynthetic pathways leading to salicinoids have yet to be defined. Here, we
Satish Kulasekaran +9 more
openaire +3 more sources
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) is a UDP-dependent galactosyltransferase [PDF]
Glycosyltransferases (GTs) are enzymes that catalyze the formation of glycosidic bonds and hundreds of GTs have been identified so far in humans. Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) has been associated with central nervous system ...
João B. Vicente +6 more
doaj +2 more sources
Characterization of UDP-glycosyltransferase family members reveals how major flavonoid glycoside accumulates in the roots of Scutellaria baicalensis [PDF]
Background Flavonoid glycosides extracted from roots of Scutellaria baicalensis exhibit strong pharmaceutical antitumor, antioxidative, anti-inflammatory, and antiviral activities.
Tianlin Pei +10 more
doaj +2 more sources
Potato (Solanum tuberosum) is a globally important staple crop. However, cultivated potato varieties are highly sensitive to low temperatures. The molecular mechanisms underlying freezing resistance in potatoes remain poorly understood.
guangtao Zhu, Li Yuan
exaly +3 more sources
Enzymatic synthesis of novel isobavachalcone glucosides via a UDP-glycosyltransferase
Glycosylation is often used to improve a natural product's properties such as water solubility, chemical stability, pharmacological potency, and structure diversification. In this study, we studied the enzymatic synthesis of novel isobavachalcone glucosides using a UDP-glycosyltransferase (YjiC) from Bacillus licheniformis DSM-13.
Hong-Mei, Li +7 more
openaire +3 more sources
Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as a potential antifungal target [PDF]
The sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) is an essential metabolite in both prokaryotes and eukaryotes. In fungi, it is the precursor for the synthesis of chitin, an essential component of the fungal cell wall.
Hurtado-Guerrero, Ramon +12 more
core +5 more sources
Stevia rebaudiana is a plant of the Asteraceae family that is used as a natural sweetener. Stevia has been shown to be safe for human consumption and has been utilised as a sweetener substitute for diabetic and obese people.
Nor Iswani Mokthar +6 more
doaj +1 more source
UDP-Glycosyltransferases in Edible Fungi: Function, Structure, and Catalytic Mechanism
UDP-glycosyltransferases (UGTs) are the most studied glycosyltransferases, and belong to large GT1 family performing the key roles in antibiotic synthesis, the development of bacterial glycosyltransferase inhibitors, and in animal inflammation.
Yumeng Yang +6 more
doaj +1 more source

