Results 101 to 110 of about 97,609 (305)

El enfoque del paradigma funcionalista en torno a la naturaleza, alcances, metas y proyecciones del proceso de reforma educacional

Revista Iberoamericana de Educación, 2008
El presente artículo provee un análisis del enfoque funcionalista en relación a tres aspectos cruciales que inciden tanto en el desarrollo de los sistemas educativos como en los procesos observables al interior de estos: a) la interrelación Estado ...
Óscar Espinoza Díaz
doaj  

Introduction. Law and political economy in Latin America: Problems and perspectives for a transnational agenda

Oñati Socio-Legal Series
This special issue examines the relationship between law and political economy in Latin America, foregrounding historically situated and context-sensitive approaches to the study of legal-economic orders.
Ricardo Valenzuela, Matías Guiloff
doaj   +1 more source

Cascade synthesis of uridine-5′-diphosphate glucuronic acid by coupling multiple whole cells expressing hyperthermophilic enzymes

Microbial Cell Factories, 2019
Background Enzymatic glycan synthesis has leapt forward in recent years and a number of glucuronosyltransferase (EC 2.4.1.17) have been identified and prepared, which provides a guide to an efficient approach to prepare glycans containing glucuronic acid
Dan-Hua Meng, Ran-Ran Du, Lu-Zhou Chen, Meng-Ting Li, Fei Liu, Jin Hou, Yi-Kang Shi, Feng-Shan Wang, Ju-Zheng Sheng   +8 more
doaj   +1 more source

Expression and characterization of MMP1090 UDP-Gal/UDP-GalNAc Epimerase and investigation into UDP-sugar assays [PDF]

, 2008
A gene found in Methanococcus maripaludis, MMP1090, is a homolog of known UDP-glucose (UDP-Glc)/UDP-galactose (UDP-Gal) and UDP-N-acetylglucosamine (UDP-GlcNAc)/UDP-Nacetylgalactosamine (UDP-GalNAc) 4-epimerases.
Nguyen, Thao
core  

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

Clinical Pharmacology &Therapeutics, EarlyView.
This study investigated genetic determinants of the pharmacokinetics of the CYP2C8 index drugs repaglinide and gemfibrozil, and their interaction in healthy participants. Sequencing data from a study with montelukast revealed a novel functional CYP2C8 allele (rs2071426, CYP2C8*19), predicted to create an intronic splice donor site.
Anssi J. H. Mykkänen, Päivi Hirvensalo, Kathrin Klein, Dorota Kaminska, Markus Grube, Tuija Tapaninen, Johanna I. Kiiski, Mikko Neuvonen, Ville T. Männistö, Jussi Pihlajamäki, Mladen Tzvetkov, Matthias Schwab, Aleksi Tornio, Janne T. Backman, Mikko Niemi   +14 more
wiley   +1 more source

O-glucosyltransferases in wheat (triticum aeshvum) and the competing weed black-grass (alopecurus myosuroides) [PDF]

, 2003
The glucosylation of xenobiotics, catalysed by UDP-glucose dependent O-Glucosyltransferases (OGTs), is a major route of pesticide metabolism in wheat {Triticum aestivum L.).
Brazier, Melissa Catherine
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Characterizing non-hydrolyzing Neisseria meningitidis serogroup A UDP-N-acetylglucosamine (UDP-GlcNAc) 2-epimerase using UDP-N-acetylmannosamine (UDP-ManNAc) and derivatives [PDF]

, 2016
Neisseria meningitidis serogroup A non-hydrolyzing uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) 2-epimerase (NmSacA) catalyzes the interconversion between UDP-GlcNAc and uridine 5'-diphosphate-N-acetylmannosamine (UDP-ManNAc).
Chen, Xi, Muthana, Musleh M, Qu, Jingyao, McArthur, John B, Zhang, Lei, Yu, Hai   +5 more
core   +1 more source

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

Drug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler, Tobias Veit, Thomas Keller, Volker Auwärter   +3 more
wiley   +1 more source

First record of the highfin goby Gobionellus oceanicus (Gobiiformes: Gobiidae) in Costa Rican freshwaters

Cuadernos de investigación UNED, 2018
The highfin goby Gobionelus oceanicus is herein reported for the first time in freshwaters of Costa Rica. One specimen was collected in the lower Pacuare River basin, Atlantic slope, Costa Rica.
Francisco S. Álvarez, Derick Herrerea, Arturo Angulo   +2 more
doaj   +1 more source

Enzymatic production of hyaluronan oligo- and polysaccharides

, 2010
Hyaluronan oligo- and polysaccharides are abundant in the human body. Depending on the chain length, hyaluronan is an important structural component or is involved in influencing cell responses during embryonic development, healing processes ...
Kooy, F.K.
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