Results 121 to 130 of about 76,789 (230)

A Survey for Deep Reinforcement Learning Based Network Intrusion Detection

Applied AI Letters, Volume 7, Issue 2, June 2026.
This paper surveys deep reinforcement learning (DRL) for network intrusion detection, evaluating model efficiency, minority attack detection, and dataset imbalance. Findings show DRL achieves state‐of‐the‐art results on public datasets, sometimes surpassing traditional deep learning.
Wanrong Yang, Alberto Acuto, Yihang Zhou, Dominik Wojtczak   +3 more
wiley   +1 more source

Uridine diphosphate drives myeloid differentiation and functional reprogramming through dynamic transcriptional network. [PDF]

Front Immunol
Giordano C, Gentile D, Straface E, Gallo R, Cristiani CM, Abatino A, Pastore A, Celano M, Arcucci A, Albano F, Falco G, Veneziano C, Santamaria G, Aversa I, Isdraele Romano L, Palmieri C, Fiume G.   +16 more
europepmc   +1 more source

Disarming the Pathogen's Metabolic Weapon: A Novel Route to Durable Disease Resistance

Modern Agriculture, Volume 4, Issue 1, June 2026.
Two routes to sugar acquisition in pathogenic bacteria and corresponding ‘pathogen‐starvation’ strategies. TAL effectors activate plant SWEET transporters to promote sucrose efflux into the apoplast, which can be blocked by editing SWEET promoter effector‐binding elements to prevent TAL binding. The T3E AvrBs2 converts host UDP‐galactose into xanthosan,
Yixuan Mi, Yuheng Yang
wiley   +1 more source

Structural insights into SetA-mediated Rab1 glucosylation and PI3P-guided localization during early <i>Legionella</i> infection. [PDF]

Proc Natl Acad Sci U S A
Im HN, Lee Y, Song Y, Hahn H, Jeon H, Shin D, Lee S, Kim KH, Kim KT, Suh SW, Jang DM, Kim HS.   +11 more
europepmc   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

A characterization of recombinant Arabidopsis FRIABLE1 (FRB1) reveals robust rhamnogalacturonan-I rhamnosyltransferase activity and critical catalytic residues. [PDF]

J Biol Chem
Robichaux KJ, Blea MN, Amos RA, Huang C, Mohnen D, Wallace IS.   +5 more
europepmc   +1 more source

Identification of resistance sources and genomic regions regulating spot blotch resistance in Asian bread wheat (Triticum aestivum L.) via genome‐wide association study

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Spot blotch (SB), caused by Bipolaris sorokiniana, is a major yield‐limiting disease of wheat (Triticum aestivum L.) in the warm, humid agroclimatic zones of South Asia. The development of resistant cultivars through molecular approaches offers a sustainable strategy for managing this disease.
Nikita Aggarwal, Xinyao He, Mukesh Rathore, Farkhandah Jan, Vikas Gupta, Reyazul Rouf Mir, Pawan K. Singh   +6 more
wiley   +1 more source

<i>De novo</i> biosynthesis of eriocitrin in <i>Saccharomyces cerevisiae</i> through deep learning-guided enzyme screening and systematic metabolic engineering. [PDF]

Synth Syst Biotechnol
Lu Q, Tan X, Zhang S, Wang Y, Zhao Y, Liu J, Hu F, Zuo S, Chen J, Fan L, Ding S, Xiao Z, Shan Y.   +12 more
europepmc   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Abad Valero, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

Structure-coevolution dual-guided engineering of C-glycosyltransferase enables high-level biosynthesis of vitexin in <i>Yarrowia lipolytica</i>. [PDF]

Synth Syst Biotechnol
Shi CQ, Chen YJ, Yang WL, Zheng S, Cai R, Hou J, Wang DQ, Sheng JZ.   +7 more
europepmc   +1 more source