Results 161 to 170 of about 211,543 (281)

Structural basis of undecaprenyl phosphate glycosylation leading to polymyxin resistance in Gram-negative bacteria. [PDF]

Nat Commun
Ashraf KU, Bunoro-Batista M, Ansell TB, Punetha A, Rosario-Garrido S, Firlar E, Kaelber JT, Stansfeld PJ, Petrou VI.   +8 more
europepmc   +1 more source

First Step Towards the Humanisation of Protein N‐Glycosylation in Chlamydomonas reinhardtii Through Heterologous Expression of α(1,2)‐Mannosidases

Plant Biotechnology Journal, EarlyView.
C. Plasson, J. Balieu, P. Lerouge, M. Bardor, E. Mathieu‐Rivet   +4 more
wiley   +1 more source

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

Plant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Mechanistic snapshots of lipid-linked sugar transfer. [PDF]

Nat Commun
Morgan RT, Motta S, Gil-Iturbe E, Bhattacharjee B, Anwar MT, Di Muccio G, Romagnoli A, Mishra B, Ashraf KU, Bang I, Di Marino D, Lowary TL, Quick M, Petrou VI, Stowell MHB, Nygaard R, Mancia F.   +16 more
europepmc   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

A structural basis for the strain-dependent UDP-sugar specificity of glycosyltransferase C from the Limosilactobacillus reuteri accessory secretion system. [PDF]

Acta Crystallogr D Struct Biol
Griffiths R, Pfalzgraf H, Latousakis D, Ashworth G, Dong C, Hemmings A, Juge N.   +6 more
europepmc   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

UDP-glucuronic acid availability underlies sex difference in renal expression of nonsulfated Human Natural Killer-1 (HNK-1) glycans. [PDF]

PLoS One
Onishi T, Okayama H, Kitano H, Higashi K, Nakagawa N, Nonaka M, Oka S, Morise J.   +7 more
europepmc   +1 more source

Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing

Plant Biotechnology Journal, EarlyView.
Haomiao Yu, Xiao Feng, Xiaohang Zheng, Xiao Wang, Wenxin Zheng, Zhizhou Zhang, Yuanyuan Jiang, Ruiwu Yang, Li Zhang, Zhaohui Zhong   +9 more
wiley   +1 more source