Results 141 to 150 of about 499,883 (421)
Aims Amgevita is a licensed biosimilar to adalimumab, having demonstrated high pharmacokinetic and clinical similarity to Humira. Switching to a lower‐cost medicine may elicit a nocebo effect, whereby expectations of poorer efficacy impact outcomes despite pharmacological similarity. This prospective cohort study examined clinical and economic outcomes
Louise Rabbitt+7 more
wiley +1 more source
Correlation Between Low Bone Density and Disease Activity in Patients with Ulcerative Colitis [PDF]
BACKGROUND Different clinical and epidemiological studies using dual-energy X-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.
Aghaei, M.+8 more
core
Application of a novel tool for diagnosing bile acid diarrhoea [PDF]
Bile acid diarrhoea (BAD) is a common disease that requires expensive imaging to diagnose. We have tested the efficacy of a new method to identify BAD, based on the detection of differences in volatile organic compounds (VOC) in urine headspace of BAD vs.
Arasaradnam+23 more
core +3 more sources
In Search of Newer Targets for IBD: A Systems and a Network Medicine Approach [PDF]
Introduction: Crohn's disease and ulcerative colitis, both under the umbrella of inflammatory bowel diseases (IBD), involve many distinct molecular processes. The difference in their molecular processes is studied by using the different genes involved in each disease, and it is explored further for drug targeting and drug repurposing.
arxiv
Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology [PDF]
Background: Clinical decision and patient care management in inflammatory bowel diseases is largely based on the assessment of clinical symptoms, while the biomarkers currently in use poorly reflect the actual disease activity.
Alexandra Touroutoglou+31 more
core +1 more source
Anatomical Region of the Colon as an Influencing Factor for Ulcerative Colitis Development
Objectives: To determine if the anatomical location and extent of ulcerative inflammation influences the primary development of ulcerative colitis by defining the primary starting locations of ulcerative inflammation processes and determining the ...
Enkhbaatar Tseden+2 more
doaj +1 more source
The safety of vedolizumab for ulcerative colitis and Crohn's disease
Objective Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the safety of vedolizumab.
J. Colombel+13 more
semanticscholar +1 more source
Surgery and Ulcerative Colitis [PDF]
The management of ulcerative colitis requires the collaboration of various teams looking after the patient and any decision regarding surgery should involve not only the patient and the surgeons but also various other professionals looking after the ...
Debono, Joseph, Gatt, Dennis
core
On the dynamics of nitrite, nitrate and other biomarkers of nitric oxide production in inflammatory bowel disease [PDF]
Nitrite and nitrate are frequently used surrogate markers of nitric oxide (NO) production. Using rat models of acute and chronic DSS-induced colitis we examined the applicability of these and other NO-related metabolites, in tissues and blood, for the ...
Ahn+81 more
core +1 more source