Results 171 to 180 of about 215,870 (306)

Multicenter experience using tofacitinib for treatment of refractory pediatric inflammatory bowel diseases in the United States

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Tofacitinib is a selective Janus kinase (JAK‐1) inhibitor approved for the treatment of ulcerative colitis (UC) in adults. Data is limited in the pediatric population. The aim of this study was to evaluate the efficacy of tofacitinib in pediatric inflammatory bowel disease (IBD).
Denise D. Young, Jennifer E. Murphy, Mallory Chavannes, Jennifer L. Dotson, Jeanne Tung, Erica Chang, Brad Pasternak, Erin Crawford, Nancy McGreal, Jonathan Moses, Sandra C. Kim   +10 more
wiley   +1 more source

Prevalence of disorders of gut–brain‐interaction in pediatric patients with in‐remission inflammatory bowel disease: An Italian multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric patients with in‐remission inflammatory bowel disease (IBD) often report persistent gastrointestinal symptoms, suggesting a potential overlap with disorders of gut–brain‐interaction (DGBIs). While DGBIs affect up to 40% of the general population, their prevalence in quiescent IBD children remains limited.
Giovanna Quatrale, Niccolo’ Chirico, Luigi Colecchia, Giuseppe Stella, Francesco Proli, Pietro Pisano, Erminia Romeo, Paola De Angelis, Licia Pensabene, Giovanni Marasco, Giovanni Di Nardo, Giovanni Barbara, Antonio Gasbarrini, Franco Scaldaferri, Valentina Giorgio   +14 more
wiley   +1 more source

Characterizing the gut virome in ulcerative colitis and crohn's disease: signatures of disease severity. [PDF]

Virol J
Daryani NE, Jazayeri SM, Izadi N, Ahmadi H, Baghi HB, Shirmohammadi M, Sabbaghian M, Shekarchi AA, Marvi SS, Azadi A, Poortahmasebi V.   +10 more
europepmc   +1 more source

Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Children with inflammatory bowel disease (IBD) have an increased risk of developing kidney disorders, which may cause significant kidney function impairment (SKI) or lead to chronic kidney disease (CKD). In this study we aimed to provide insights in causes and diagnoses of SKI cases and to provide recommendations for pediatric ...
Stephanie A. Vuijk, Renz C. W. Klomberg, Tobias Schwerd, Anne M. Griffiths, Séamus Hussey, Matthew W. Carroll, Petter Malmborg, Protima Deb, Margreet Wessels, Natalia Mouratidou, Stephanie van Biervliet, Michael Friedt, Susie Minson, Femke H. M. Vrieling‐Prince, Nicholas M. Croft, Lissy de Ridder, the PIBD‐SETQuality Safety Registry collaborative group   +16 more
wiley   +1 more source

Fecal microbiota transplantation in ulcerative colitis: evidence, mechanisms, and practice considerations. [PDF]

Ther Adv Gastroenterol
Liu J, Wu X.
europepmc   +1 more source

Severe allergic reaction to ustekinumab reinitiation in a pediatric patient with Crohn's disease: A case report

JPGN Reports, EarlyView.
Abstract Ustekinumab (UST) is a monoclonal antibody used in the management of moderate to severe inflammatory bowel disease. While generally well‐tolerated, serious adverse reactions, including hypersensitivity and anaphylaxis, have been documented, specifical following the initial intravenous (IV) dose.
Kennedy Sparling, Shauna Schroeder, Brad Pasternak   +2 more
wiley   +1 more source

Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis: Modulating Crotonylation in Ulcerative Colitis. [PDF]

Exploration (Beijing)
Liu T, Lin B, Zhang Y, Su J, Hu X, Wang X, Liu EH, Liu S.   +7 more
europepmc   +1 more source

Serological immunity against vaccine‐preventable diseases in children with inflammatory bowel disease at diagnosis

JPGN Reports, EarlyView.
Abstract Objectives Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine‐preventable diseases. However, vaccination coverage in this population is often suboptimal. This retrospective study assessed the vaccination status and vaccine serology of children diagnosed with IBD in a high‐income country with broad vaccine access ...
Clara Noble, Renato Gualtieri, Klara Posfay‐Barbe, Nathalie Rock, Geraldine Blanchard‐Rohner   +4 more
wiley   +1 more source

Prediction of Relapse and Steroid Dependency in Pediatric Ulcerative Colitis. [PDF]

Medicina (Kaunas)
Onder M, Ecevit CO, Pelek S, Demirtas Guner D, Eren G, Cakar S, Bekem O.   +6 more
europepmc   +1 more source

Responsible laboratory surveillance of pediatric patients with inflammatory bowel disease on biologic infusion therapy

JPGN Reports, EarlyView.
Abstract The annual healthcare spending on pediatric inflammatory bowel disease (IBD) has increased over time. The objectives of the study were to investigate the cost of routine laboratory surveillance in pediatric IBD patients during outpatient maintenance biologic infusions and determine their impact on clinical management.
Tanmai Shah, Ashwin Agrawal, Héctor E. Alcalá, Anupama Chawla   +3 more
wiley   +1 more source