Results 111 to 120 of about 2,019,877 (178)

Structure and regulatory mechanism of human uncoupling protein 1

open access: yes
Uncoupling protein 1 (UCP1) in the mitochondrial inner membrane is responsible for the thermogenic properties of brown adipose tissue. In response to cold exposure, UCP1 is activated by free fatty acids and catalyses proton leak, dissipating the proton motive force, which mitochondria use to drive ATP synthesis.
openaire   +2 more sources

Brown Adipose Tissue—A Therapeutic Target in Obesity?

open access: yesFrontiers in Physiology, 2018
Paul Trayhurn, Paul Trayhurn
doaj   +1 more source

Bile acids induce uncoupling protein 1-dependent thermogenesis and stimulate energy expenditure at thermoneutrality in mice.

open access: yesAmerican Journal of Physiology. Endocrinology and Metabolism, 2016
Marika Ziętak, L. Kozak
semanticscholar   +1 more source

Exposure to PCB52 (2,2',5,5'-tetrachlorobiphenyl) blunts induction of the gene for uncoupling protein 1 (UCP1) in white adipose. [PDF]

open access: yesEnviron Toxicol Pharmacol
Gourronc FA   +10 more
europepmc   +1 more source

p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.

open access: yesAmerican Journal of Physiology. Endocrinology and Metabolism, 2016
P. Hallenborg   +14 more
semanticscholar   +1 more source

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