Effects of Quercetin Metabolites on Glucose‐Dependent Lipid Accumulation in 3T3‐L1 Adipocytes
Molecular Nutrition &Food Research, EarlyView.Quercetin metabolites (QMs), found in foods like fruits and vegetables, can influence how fat cells process fats and sugars. This study shows that QMs help reduce fat storage and sugar uptake in fat cells when sugar levels are high. Under conditions mimicking caloric restriction, they boost sugar use for energy.
Marco Rendine +7 more
wiley +1 more source
Redox BiologyAvailable evidence indicates that neuregulin-1 (NRG-1) can provide a protection against myocardial ischemia/reperfusion (I/R) injury and is involved in various cardioprotective interventions by potential regulation of mitophagy.
Xin-Tao Li +9 more
doaj
The effects of the overexpression of recombinant uncoupling protein 2 on proliferation, migration and plasminogen activator inhibitor 1 expression in human vascular smooth muscle cells [PDF]
, 2005 Jeong‐Yeol Park +12 more
openalex +1 more source
Addendum to: Anti-obesity Effects of Artemisia annua Extract in Zucker Fatty Rats and High-Fat Diet Sprague Dawley Rats through Upregulation of Uncoupling Protein 1 (J Obes Metab Syndr 2021;30:32-43). [PDF]
J Obes Metab Syndr, 2022 Choi EY +6 more
europepmc +1 more source
PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis
Molecular Nutrition &Food Research, EarlyView.Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
wiley +1 more source
Leptin Is Required for Uncoupling Protein-1-Independent Thermogenesis during Cold Stress [PDF]
, 2006 Jozef Ukropec +3 more
openalex +1 more source
The role of gut microbiota‐derived metabolites in neuroinflammation
Neuroprotection, EarlyView.Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley +1 more source
Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria [PDF]
, 2006 Telma C. Esteves +2 more
openalex +1 more source
Anti-Obesity Effects of Artemisia annua Extract in Zucker Fatty Rats and High-Fat Diet Sprague Dawley Rats through Upregulation of Uncoupling Protein 1. [PDF]
J Obes Metab Syndr, 2021 Choi EY +6 more
europepmc +1 more source
Obesity, EarlyView.Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian +17 more
wiley +1 more source