Results 301 to 310 of about 1,699,867 (343)

Upregulated NOTCH2 Expression Is Implicated in the Clinical Aggressiveness of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma

International Journal of Dermatology, EarlyView.
ABSTRACT Background Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) represent clinicopathological variants of a spectrum. It is known that AFX and PDS tumors harbor frequent NOTCH1/2 mutations. However, the expression of Notch signaling pathway‐associated proteins in both tumor cells has not been studied before.
Yi‐Pei Lee, Fahimeh Razegphpour, Emilia Sorescu, Markus Stücker, Thilo Gambichler   +4 more
wiley   +1 more source

Litter sex composition influences plasma prolactin levels but not the melanin‐concentrating hormone immunoreactive neurons in the medial preoptic area of late lactating Long‐Evans rats

Journal of Neuroendocrinology, EarlyView.
Influence of litter sex composition on maternal prolactin levels and MCH‐immunoreactive (MCH‐ir) neurons in the vmMPOA of lactating rats. The sex ratio of litters affects maternal physiology, specifically increasing prolactin levels and altering weight gain patterns, while food and water intake and MCH‐ir neuron counts remain unchanged.
Ammir Y. Helou, Camila de Carvalho, Larissa A. do Carmo, Jackson C. Bittencourt   +3 more
wiley   +1 more source

The Hydroxyl at Position C1 of Genipin Is the Active Inhibitory Group that Affects Mitochondrial Uncoupling Protein 2 in Panc-1 Cells

, 2016
Yang Yang, Yifu Yang, Jianwei Hou, Yue Ding, Tong Zhang, Yong Zhang, Jianying Wang, Chenchen Shi, Wenwei Fu, Zhenzhen Cai   +9 more
openalex   +2 more sources

Skin development in the gray short‐tailed opossum (Monodelphis domestica)—From skin respiration to thermoregulation

Journal of Anatomy, EarlyView.
The skin development in the gray short‐tailed opossum (Monodelphis domestica) has been examined using histological, morphometric, and μCT methods. During a long period of postnatal development, the structural differentiation of the skin results in a functional shift from transcutaneous gas exchange to thermoregulation in later life. Abstract Marsupials
Kirsten Ferner
wiley   +1 more source

Results Tables from Here and there, but not everywhere: repeated loss of uncoupling protein 1 in amniotes

, 2016
Suzanne E. McGaugh, Todd A. Schwartz
openalex   +2 more sources

Gene Expression Shifts in Emperor Penguin Adaptation to the Extreme Antarctic Environment

Molecular Ecology, EarlyView.
ABSTRACT Gene expression can accelerate ecological divergence by rapidly tweaking the response of an organism to novel environments, with more divergent environments exerting stronger selection and supposedly, requiring faster adaptive responses. Organisms adapted to extreme environments provide ideal systems to test this hypothesis, particularly when ...
Josephine R. Paris, Flávia A. Nitta Fernandes, Federica Pirri, Samuele Greco, Marco Gerdol, Alberto Pallavicini, Marine Benoiste, Clément Cornec, Lorenzo Zane, Brian Haas, Céline Le Bohec, Emiliano Trucchi   +11 more
wiley   +1 more source

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling

, 2017
Shannon H. Carroll, Ellen Zhang, Bing F. Wang, Katherine B. LeClair, Arifeen Rahman, David E. Cohen, Jorge Plutzky, Parth Patwari, Richard Lee   +8 more
openalex   +2 more sources

Evidence of Intraspecific Adaptive Variation in the American Pika (Ochotona princeps) on a Continental Scale Using a Target Enrichment and Mitochondrial Genome Skimming Approach

Molecular Ecology, EarlyView.
ABSTRACT Montane landscapes present an array of abiotic challenges that drive adaptive evolution amongst organisms. These adaptations can promote habitat specialisation, which may heighten the risk of extirpation from environmental change. For example, higher metabolic rates in an endothermic species may contribute to heightened cold tolerance, whilst ...
Zachery M. Farrand, Kurt E. Galbreath, Katherine C. Teeter   +2 more
wiley   +1 more source

Molecular bases of mitochondrial uncoupling protein 1 induced thermogenesis

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018
Florian Accettella, Sandrine Masscheleyn, Fabrice Giusti, Karine Moncoq, Manuela Zoonens, Bruno Miroux, Mathilde S. Piel   +6 more
openaire   +2 more sources

Mixed Outcomes in Recombination Rates After Domestication: Revisiting Theory and Data

Molecular Ecology, EarlyView.
ABSTRACT The process of domestication has altered many phenotypes. Selection on these phenotypes has long been hypothesised to indirectly select for increases in the genome‐wide recombination rate. This hypothesis is potentially consistent with theory on the evolution of the recombination rate, but empirical support has been unclear. We review relevant
Madeline Bursell, Manav Rohilla, Lucia Ramirez, Yuhuan Cheng, Enrique J. Schwarzkopf, Rafael F. Guerrero, Caiti Smukowski Heil   +6 more
wiley   +1 more source