Results 321 to 330 of about 1,699,867 (343)

Skeletal muscle mitochondrial correlates of critical power and W' in healthy active individuals

Experimental Physiology, EarlyView.
Abstract The asymptote (critical power; CP) and curvature constant (W') of the hyperbolic power–duration relationship can predict performance within the severe‐intensity exercise domain. However, the extent to which these parameters relate to skeletal muscle mitochondrial content and respiratory function is not known.
Donald L. Peden, Robert Rogers, Emma A. Mitchell, Suzanne M. Taylor, Stephen J. Bailey, Richard A. Ferguson   +5 more
wiley   +1 more source

Pig has no uncoupling protein 1

Biochemical and Biophysical Research Communications, 2017
Brown adipose tissue (BAT) is critical for mammal's survival in the cold environment. Uncoupling protein 1 (UCP1) is responsible for the non-shivering thermogenesis in the BAT. Pig is important economically as a meat-producing livestock. However, whether BAT or more precisely UCP1 protein exists in pig remains a controversy. The objective of this study
Lianjie Hou, Jia Shi, Lingbo Cao, Guli Xu, Chingyuan Hu, Chong Wang   +5 more
openaire   +4 more sources

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Cloning and ontogenetic expression of the uncoupling protein 1 gene UCP1 in sheep

Journal of Applied Genetics, 2012
The uncoupling protein 1 (UCP1) is an indicator of brown adipocytes and is involved in the control of body temperature and regulation of energy balance. It abundantly expresses in newborns and has important functions in adults. However, little information was known on UCP1 gene expression in young and adolescent sheep.
Jianliang Wu, Wenzhong Liu, Liying Qiao, Yanan Yuan, Jianhua Liu   +4 more
openaire   +4 more sources

Fish Oil Protects Wild Type and Uncoupling Protein 1‐Deficient Mice from Obesity and Glucose Intolerance by Increasing Energy Expenditure

Molecular Nutrition & Food Research, 2019
SCOPE The mechanisms and involvement of uncoupling protein 1 (UCP1) in the protection from obesity and insulin resistance induced by intake of a high-fat diet rich in omega-3 (n-3) fatty acids are investigated. METHODS AND RESULTS C57BL/6J mice are fed
Tiago E. Oliveira, Érique Castro, Thiago Belchior, M. L. Andrade, A. Chaves-Filho, A. Peixoto, Mayara F Moreno, Milene Ortiz-Silva, R. Moreira, Alex Inague, M. Yoshinaga, S. Miyamoto, N. Moustaid‐Moussa, William T. Festuccia   +13 more
semanticscholar   +1 more source

Uncoupling Proteins 1 and 3 Are Regulated Differently

Biochemistry, 2000
Using a heterologous yeast expression system, we have previously found a marked discordance between the effects of uncoupling protein (UCP) 1 and UCP3L on basal O(2) consumption in whole yeast versus isolated mitochondria. In whole yeast, UCP3L produces a greater stimulation of basal O(2) consumption, while in isolated mitochondria, UCP1 produces a ...
Thilo Hagen, Chen-Yu Zhang, Bradford B. Lowell, Claudia R. Vianna   +3 more
openaire   +3 more sources

A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast

Biochemical Journal, 2001
Uncoupling protein 1 (UCP1) from mouse was expressed in yeast and the specific (GDP-inhibitable) and artifactual (GDP-insensitive) effects on mitochondrial uncoupling were assessed. UCP1 provides a GDP-inhibitable model system to help interpret the uncoupling effects of high expression in yeast of other members of the mitochondrial carrier protein ...
Martin D. Brand, Kevin M. Brindle, Mika B. Jekabsons, Jeffrey A. Stuart, James A. Harper   +4 more
openaire   +3 more sources

Uncoupling protein 1 expression and high-fat diets

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2011
Uncoupling protein 1 (Ucp1) is the key component of β-adrenergically controlled nonshivering thermogenesis in brown adipocytes. This process combusts stored and nutrient energy as heat. Cold exposure not only activates Ucp1-mediated thermogenesis to maintain normothermia but also results in adaptive thermogenesis, i.e., the recruitment of thermogenic ...
Tobias Fromme, Martin Klingenspor
openaire   +2 more sources

Expression of uncoupling protein 1 in bovine muscle cells1

Journal of Animal Science, 2016
Uncoupling protein 1 (Ucp1) is predominantly expressed in brown/beige adipocytes in mammals. Although myogenic cells have been suggested to commit to a brown adipocyte lineage through the induction of Prdm16 expression, Prdm16 is also expressed in skeletal muscle. Thus, we examined expression of Ucp1 in bovine myogenic cells. Considering that Ucp1 is a
Masayuki Funaba, Masaru Murakami, Tohru Matsui, Hirofumi Ohtsuki, Yuhang Qiao, Yohei Kanamori, Osamu Hashimoto, Ken Onda, Shozo Tomonaga, M A Abd Eldaim, Reiichiro Sato, Tomoya Yamada   +11 more
openaire   +3 more sources

CREG1 promotes uncoupling protein 1 expression and brown adipogenesis in vitro

Journal of Biochemistry (Tokyo), 2018
Brown adipocytes play a critical role for adaptive thermogenesis to regulate body temperature in cold or to circumvent diet-induced obesity. In this study, we investigated the role of cellular repressor of E1A-stimulated genes 1 (CREG1) on brown ...
Tatsuya Kusudo, M. Hashimoto, N. Kataoka, Yongxue Li, Aya Nozaki, H. Yamashita   +5 more
semanticscholar   +1 more source