Misfolded proteins in the endoplasmic reticulum (ER) activate the unfolded protein response (U PR), which enhances protein folding to restore homeostasis.
Aviram +87 more
core +1 more source
SKN-1/Nrf, a new unfolded protein response factor? [PDF]
Keith P Choe, Chi K Leung
doaj +1 more source
The unfolded protein response signaling pathways in molluscs
Unfolded protein response (UPR) as collective signal transduction pathways is essential for surviving the endoplasmic reticulum (ER) stress in vertebrates and invertebrates.
Y Huang, J Sun, L Wang, L Song
doaj
Identification of ERSE-II, a New cis-Acting Element Responsible for the ATF6-dependent Mammalian Unfolded Protein Response [PDF]
Koichi Kokame +2 more
openalex +1 more source
Developmental hypomyelination in Wolfram syndrome: New insights from neuroimaging and gene expression analyses [PDF]
Wolfram syndrome is a rare multisystem disorder caused by mutations in WFS1 or CISD2 genes leading to brain structural abnormalities and neurological symptoms. These abnormalities appear in early stages of the disease.
Dougherty, Joseph +7 more
core +1 more source
Unfolded protein responses in T cell immunity
Endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) are integral to T cell biology, influencing immune responses and associated diseases. This review explores the interplay between the UPR and T cell immunity, highlighting the role of these cellular processes in T cell activation, differentiation, and function.
Wencan Zhang, Xu Cao
openaire +3 more sources
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response [PDF]
Kyosuke Haze +6 more
openalex +1 more source
A survival pathway forCaenorhabditis eleganswith a blocked unfolded protein response [PDF]
Fumihiko Urano +6 more
openalex +1 more source
Orchestrating the unfolded protein response in health and disease [PDF]
Randal J. Kaufman
openalex +1 more source

