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Sphingolipids and the unfolded protein response
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019The unfolded protein response (UPR) is a response by the endoplasmic reticulum to stress, classically caused by any disruption to cell homeostasis that results in an accumulation in unfolded proteins. However, there is an increasing body of research demonstrating that the UPR can also be activated by changes in lipid homeostasis, including changes in ...
Bennett, M.K. +2 more
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Control of immune cell function by the unfolded protein response
Nature Reviews Immunology, 2023Di Conza Giusy +2 more
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Mechanisms, regulation and functions of the unfolded protein response
Nature Reviews Molecular Cell Biology, 2020Claudio Hetz +2 more
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Mitochondriálnà "unfolded protein response".
2016Mitochondrion is an organelle of the eukaryotic cell responsible for the crucial metabolic processes and the apoptosis. Therefore, it is necessary for the survival of the cell to maintain mitochondrial functionality. Hence, the mitochondria have specific signalling stress-activated pathways for re-establishing its homeostasis. Unfolded protein response
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The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging
Cell Metabolism, 2023Danica Chen
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The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Nature Reviews Molecular Cell Biology, 2012Claudio Hetz
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Signal integration in the endoplasmic reticulum unfolded protein response
Nature Reviews Molecular Cell Biology, 2007David Ron, Peter Walter
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