Osmotically balanced, large unilamellar liposomes that enable sustained bupivacaine release for prolonged pain relief in in vivo rat models. [PDF]
Sci Rep, 2021 To efficiently prolong analgesic effects, we developed osmotically balanced, large unilamellar liposomes (~ 6 μm in diameter) in which highly concentrated bupivacaine (up to 30 mg/mL) was encapsulated, and their sustained bupivacaine release was highly ...
Yoo H, Park JS, Oh SS, Kang H.
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Encapsulation of Hydrophobic Apigenin into Small Unilamellar Liposomes Coated with Chitosan Through Ethanol Injection and Spray Drying. [PDF]
Food Bioproc Tech, 2023 Despite the multiple health benefits, natural flavonoid apigenin has poor aqueous solubility that restricts its delivery in foods. This study investigated the potential of spray-dried chitosan-coated liposomes prepared from scalable methods for the food ...
Ang SS, Thoo YY, Siow LF.
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Functionalization and higher-order organization of liposomes with DNA nanostructures
Nature Communications, 2023 Small unilamellar vesicles (SUVs) are indispensable model membranes, organelle mimics, and drug and vaccine carriers. However, the lack of robust techniques to functionalize or organize preformed SUVs limits their applications.
Zhao Zhang +5 more
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Study of the influence of ascorbyl palmitate and amiodarone in the stability of unilamellar liposomes [PDF]
Molecular membrane biology, 2014 Amiodarone (AMI) is a low water-solubility drug, which is very useful in the treatment of severe cardiac disease. Its adverse effects are associated with toxicity in different tissues.
Luciano A. Benedini +5 more
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Monascus Red Pigment Liposomes: Microstructural Characteristics, Stability, and Anticancer Activity
Foods, 2023 Monascus red pigments (MRPs), which are a kind of natural colorant produced by Monascus spp., are widely used in the food and health supplements industry but are not very stable during processing and storage.
Pengcheng Long +10 more
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Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro [PDF]
Biochemical Journal, 1980 Small unilamellar neutral, negatively and positively charged liposomes composed of egg phosphatidylcholine, various amounts of cholesterol and, when appropriate, phosphatidic acid or stearylamine and containing 6-carboxyfluorescein were injected into ...
Christopher Kirby +2 more
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Interaction of antibody-bearing small unilamellar liposomes with target free antigen in vitro and in vivo. Some influencing factors [PDF]
Biochemical Journal, 1981 Affinity chromatography-purified and non-purified rabbit immunoglobulin G (IgG) raised against human immunoglobulin M (IgM) or kappa chain was incorporated into carboxyfluorescein-containing small unilamellar liposomes composed of egg phosphatidylcholine,
Gregory Gregoriadis +2 more
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Generation of Giant Unilamellar Liposomes Containing Biomacromolecules at Physiological Intracellular Concentrations using Hypertonic Conditions [PDF]
ACS Synthetic Biology, 2014 Artificial cells, particularly cell-sized liposomes, serve as tools to improve our understanding of the physiological conditions of living cells. However, such artificial cells typically contain a more dilute solution of biomacromolecules than that found
Kei Fujiwara, Miho Yanagisawa
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In Vitro Evaluation of the Activity of Gemcitabine-Loaded Pegylated Unilamellar Liposomes Against Papillary Thyroid Cancer Cells~!2010-04-18~!2010-06-27~!2010-08-23~! [PDF]
, 2010 Papillary carcinoma is the most common form of malignant thyroid tumor. At present, a subset of these tumors are poorly responsive to the current treatment. Gemcitabine is a pyrimidine analog active against different types of solid tumors, but its use is
Margherita Vono +6 more
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Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock [PDF]
Langmuir, 2015 Giant unilamellar vesicles (GUVs), composed of a phospholipid bilayer, are often used as a model system for cell membranes. However, the study of proteo-membrane interactions in this system is limited as the incorporation of integral and lipid-anchored ...
Isabelle Motta +6 more
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