M2e-Based Influenza Vaccines with Nucleoprotein: A Review
Vaccines, 2021 Discovery of conserved antigens for universal influenza vaccines warrants solutions to a number of concerns pertinent to the currently licensed influenza vaccines, such as annual reformulation and mismatching with the circulating subtypes.
Mei Peng Tan +3 more
doaj +1 more source
Production and purification of chimeric HBc virus-like particles carrying influenza virus LAH domain as vaccine candidates [PDF]
, 2017 Background: The lack of a universal influenza vaccine is a global health problem. Interest is now focused on structurally conserved protein domains capable of eliciting protection against a broad range of influenza virus strains.
Akopjana, I +19 more
core +4 more sources
Effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom : 2014/15 end of season results [PDF]
, 2015 The 2014/15 influenza season in the United Kingdom (UK) was characterised by circulation of predominantly antigenically and genetically drifted influenza A(H3N2) and B viruses.
Andrews, N. +22 more
core +1 more source
The prospects and challenges of universal vaccines for influenza [PDF]
Trends in Microbiology, 2013 Vaccination is the most effective way to reduce the impact of epidemic as well as pandemic influenza. However, the licensed inactivated influenza vaccine induces strain-specific immunity and must be updated annually. When novel viruses appear, matched vaccines are not likely to be available in time for the first wave of a pandemic.
Kanta, Subbarao, Yumiko, Matsuoka
openaire +2 more sources
Universal influenza vaccines: from viruses to nanoparticles
Expert Review of Vaccines, 2018 Introduction: The current seasonal influenza vaccine confers only limited protection due to waning antibodies or the antigenic shift and drift of major influenza surface antigens. A universal influenza vaccine which induces broad cross-protection against
Ye Wang +3 more
doaj +1 more source
Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins
Vaccines, 2019 Vaccination is still the most efficient way to prevent an infection with influenza viruses. Nevertheless, existing commercial vaccines face serious limitations such as availability during epidemic outbreaks and their efficacy. Existing seasonal influenza
Seyed Davoud Jazayeri, Chit Laa Poh
doaj +1 more source
npj Vaccines, 2022 There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard +6 more
doaj +1 more source
The rise of companies from emerging markets in global health governance: opportunities and challenges [PDF]
, 2014 The article analyses the involvement of pharmaceutical companies from emerging markets in global health governance. It finds that they play a central role as low-cost suppliers of medicines and vaccines and, increasingly, new technologies.
ANNE ROEMER-MAHLER +23 more
core +1 more source
Protection against H1N1 influenza challenge by a DNA vaccine expressing H3/H1 subtype hemagglutinin combined with MHC class II-restricted epitopes [PDF]
, 2010 Background Multiple subtypes of avian influenza viruses have crossed the species barrier to infect humans and have the potential to cause a pandemic.
Lei Tan +6 more
core +2 more sources
Annual Universal Influenza Vaccination: Ready or Not? [PDF]
Clinical Infectious Diseases, 2006 Influenza causes annual worldwide epidemics of respiratory disease. Currently, the United States and many other countries recommend influenza vaccination for persons who are at high risk for influenza-related complications. This commentary explores the potential benefits of a policy advocating universal annual influenza vaccination and outlines ...
Bruce Gellin +4 more
openaire +2 more sources